Stable cell lines carrying a reporter gene (a tag or a fluorescent protein) cassette using CRISPR targeted genome editing via the HDR pathway is a powerful tool for monitoring endogenous target gene expression or biological processes without disrupting the target gene in vitro. https://www.creative-biogene.com/Services/Stable-Knock-in-Cell-Line-Generation/Reporter-Genes-Knock-In-Cell-Line-Generation.html
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