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Overexpression of human kynurenine-3-monooxygenase protects against 3-hydroxykynurenine-mediated

from Life Sciences Collection

Overexpression of human kynurenine-3-monooxygenase protects against 3-hydroxykynurenine-mediated apoptosis through bidirectional nonlinear feedback. Kynurenine 3-monooxygenase (KMO) is the expression product of the KMO (gene). It participates in tryptophan metabolism through the kynurenine catabolic pathway. It serves as an important branch point in the kynurenine pathway and, as a result, is an attractive drug target for immunological, neurodegenerative, and neuroinflammatory diseases. https://www.bocsci.com/tag/kynurenine-3-monooxygenase-kmo-404.html

about 3 months ago

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