LabTube.tv
  • settings
  • CC
  • 360p
  • 480p
  • 720p
  • 1080p
154 VIEWS | 0 LIKES

HDX for understanding a protein's higher order structure and function | Behind the Science

from Waters Corporation

How do researchers understand how proteins interact in the body? In #BehindtheScience, Jen meets Waters principal scientist Keith Fadgen. He compares two techniques, x-ray crystallography and hydrogen-deuterium exhange (HDX). X-ray crystallography can be used to determine the atomic and molecular structure of a crystal. HDX can be used to study protein-protein interactions over a course of time, which is useful for common biopharmacuetical studies such as epitope mapping, formulation stability testing, and understanding how diseases and viruses function. Keith explains how Waters collaborated with academic labs to make HDX experiments robust and reliable.

about 3 months ago

Recommended Videos

We've updated our Privacy Policy to make it clearer how we use your personal data.

We use cookies to provide you with a better experience, read our Cookie Policy