Exploring multiple dimensions in the forensics of “space candy” with Boston U | Behind the Science, S3 Ep3

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May 25, 2018

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  • In forensic toxicology laboratories, the accuracy and precision of an analytical technique are essential in determining what drugs or chemicals may have played a role in an individual's death. In #BehindtheScience, Jen travels to Boston University's outdoor research facility, where grad students and law enforcement are trained on crime scene investigation. Is it possible to use one analytical technique to test a variety of different matrices - liquid or solid?

    Sabra Botch-Jones, an assistant professor at Boston University School of Medicine's Biomedical Forensic Sciences department, joins Claude Mallet of Waters in the analytical laboratory. They show Jen a protocol to tests solid samples, starting with homogenization to convert the solid into a liquid, followed by extraction, then analysis by multidimensional chromatography, or 2DLC, to identify what drugs to target for analysis.

    See their full scientific method in our application note: http://www.waters.com/2Danalysis

    Watch our first episode with Sabra and Claude on how forensic laboratories use 2DLC, or LCxLC. https://www.youtube.com/watch?v=CSpzwSAIaLM

    See 2D LC instrument from Waters:
    http://www.waters.com/waters/ACQUITY-UPLC-2D-LC-multidimensional-LC/nav.htm?cid=10203030&locale=101

    Boston University School of Medicine's Forensics program:
    https://www.bu.edu/academics/gms/programs/biomedical-forensic-sciences/

    ChromatographyForensic ScienceMass Spectrometry

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