Do guard columns work? | Trust Your Science 14

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Waters Corporation

Do guard columns work? Are they really worth the investment? Guard columns can be beneficial when you're working with dirty samples and can extend column lifetime. However, some scientists avoid using guard columns because they're concerned about how they affect chromatography or if they increase time for an analytical run, as well as the added cost. Kim and Jon test a set if analyses with a guard and without, using a big injection of a dirty sample to see the difference in #TrustYourScience. Guard columns from Waters: https://www.waters.com/vanguard