Members of ABC superfamily use ATP as energy source, which allows them to pump substrates against a concentration gradient. Drugs can be simultaneously substrates or inhibitors of more than one efflux transporter, suggesting that ABC transporters employ a combined role in detoxification at above organs. https://www.creative-biogene.com/Services/Drug-Discovery-Services/ABC-transporters-Screening-and-Profilin-Assays.html
BioprocessingCell Science