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Plasma free Metanephrines Quantitation with Automated Online Sample Preparation and a LCMS Method

from Chromatography & Mass Spectrometry Solutions

Plasma free Metanephrines Quantitation with Automated Online Sample Preparation and a LCMS Method Speaker: Xiang (Kevin) He, Ph.D. - Strategic Marketing Specialist Xiang (Kevin) He presents his scientific poster about a fast, automated and analytically sensitive LC-MS/MS method developed to quantify plasma metanephrines with significantly simplified sample preparation procedure by using Thermo Scientific TurboFlow™ Technology. Unlike traditional HPLC technology, which is limited by its parabolic flow profile, the Thermo Scientific patented TurboFlow technology promotes turbulence in a packed column bed. TurboFlow technology forces streams of fluid through the column so that the mobile phase is moving so rapidly that it creates vacillating eddies. This turbulent flow motion supports a more uniform velocity profile across the diameter of the column. In this way, turbulent flow chromatography controls effective diffusion of the solutes, allowing molecules to move quickly into and out of the pores and packing particles. By using a combination of proprietary packings and technology, extremely high flow separations with no high back pressure issues can be achieved. Since turbulent flow chromatography is not limited by diffusion, the results are faster, sharper chromatographic peaks, superior to those offered by conventional chromatography.

about 7 years ago

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