How Heat Can Increase The Solvent Removal Process



January 30, 2024

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  • How Heat Can Increase The Solvent Removal Process The solvent removal step is arguably the most time consuming part of preparing your test samples for analysis, especially when completed by hand. Lab techs can sit there for hours just holding a stream of nitrogen over liquid samples to concentrate them down enough to analyze and test. The longer it takes to evaporate samples, the less a lab can process. Fewer samples processed leads to a decrease in productivity and throughput. A decrease in productivity leads to a decrease in profits. All the while, lab technicians are dealing with frustration and a lack of job satisfaction as they sit for hours watching solvent evaporate. Nitrogen gas alone can only evaporate liquid samples so fast. Increasing the gas flow may help to a point, but can lead to solvent splashing and loss of sample. Trying to hold the nitrogen stream closer to the sample’s surface will only lead to the same issue. This is the rut that many labs stay in for years, but there’s a better way. Adding a source of heat to test samples can significantly increase the rate of evaporation. As nitrogen gas blows down on the solvent, it decreases the energy and slows down the movement of the molecules within the sample. This decreases the ability of the molecules to vaporize and break away from the sample, slowing down the evaporation rate. The addition of heat re-energizes the sample and increases the movement of the solvent molecules, therefore increasing their ability to be vaporized. The combination of the two methods creates an optimal environment for efficient sample concentration, leading to a more efficient workflow. For a more hands-off approach, many labs choose to use sample evaporation equipment which combine the nitrogen blowdown technology with a heat source. These pieces of equipment are often referred to as “nitrogen evaporators”, and are designed to automate the solvent removal process by having a sample holder that can fit a number of tubes at once. Technicians no longer have to sit there for hours holding one test tube at a time, leading to higher productivity. To learn more ways to speed up or automate your lab’s sample preparation process, visit us at, or speak to our team at Summer Nights: Music from #Uppbeat (free for Creators!): License code: 2NWMWPKHEDEOSQ0R

    Analytical TechniquesChromatographyEnvironmental ScienceMass Spectrometry

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