Multiple stages in the biotherapeutics R&D pipeline require analysis of protein-protein and other biomolecular interactions, whether in the form of high-throughput screening or in-depth characterization. Static and dynamic light scattering are versatile, label-free, immobilization-free techniques that provide unique insights for a broad range of interactions. In Part I of this webinar series we present a high-throughput, automated dynamic light scattering tool for accomplishing these measurement tasks, and review how it is employed at each stage.
Topics covered:
-High-throughput screening of interactions using a dynamic light scattering plate reader (HTS-DLS)
-HTS-DLS applications in the R&D pipeline, especially developability/pre-formulation and formulation