Cas9: Gene Activation

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Wyss Institute for Biologically Inspired Engineering at Harvard University

In this technical animation, Wyss Institute researchers instruct how they engineered a Cas9 protein to create a powerful and robust tool for activating gene expression. The novel method enables Cas9 to switch a gene from off to on and has the potential to precisely induce on-command expression of any of the countless genes in the genomes of yeast, flies, mice, or humans.

More information: http://wyss.harvard.edu/viewpressrelease/192/