iPS-based Automated Drug Screening: From Human iPS to Midbrain Dopaminergic Neurons



June 19, 2014

We provide an overview over our methods allowing us to differentiate human neural precursor cells generated from iPS cultures into midbrain dopaminergic neurons in a fully automated fashion. The resulting cell cultures can serve as a scalable disease model for familial Parkinson's disease based on a LRRK2 2019S mutation and allows for screening compounds in a human neural model system.

BioengineeringStem Cells

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