Effects of Nickel and Hypoxia on Histone Methylation and Gene Expression: From Cultured Cells to Human Population Study

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SELECTBIO

The genome-wide changes of histone methylation and gene expression were analyzed in human lung cells following Nickel and Hypoxia exposure. The study of histone modification in human peripheral blood mononuclear cells indicates an association between the occupational nickel exposure and the alteration of histone modification.