Chemical Proteomics: Drug Targets, Drug Selectivity, MoA and Resistance

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SELECTBIO

This presentation gives examples for how mass spectrometry based chemical proteomics can aid at various stages in the drug discovery process including the identification of new drug targets, the selectivity of kinase inhibitors, the elucidation of the mechanism of action of drugs targeting HSP90 and identify mechanisms of resistance against targeted kinase inhibitors.