An Integrated System Using Peptide Arrays to Assess Kinase and Nuclear Receptor Activities in Clinical Samples for Biomarker Development

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SELECTBIO

Bertrand Jordan, Advisor, Aix-Marseille University (AMU)

Abstract
A system developed around peptide microarrays allows real-time measurement of phosphorylations or interactions, with sophisticated software for data acquisition and interpretation. It is applied to kinase activity profiling and nuclear receptor-coregulator interactions, in order to develop biomarkers and diagnostic applications.