Acetylated Histone H2A.Z is a Key Feature of Enhancers and the Promoters of Both Active and Bivalent Genes in Mouse ESCs

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November 26, 2012

Colyn Crane-Robinson, Professor, University of Portsmouth

Abstract
The epigenetic landscape of the histone variant H2A.Z, both acetylated and non-acetylated, is determined in mouse ESCs using ChIP-Seq. AcH2A.Z is present at the promoters of both active and poised (bivalent) genes and correlates with histone H3K4me3.

Genomics

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