Screening for Chemical Tools: Considerations on Compound Screening Collections, Assay Development and High-throughput Screening

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SELECTBIO

Dominique Audenaert, Manager Compound Screening Facility (CSF), VIB - Ghent University

Abstract
In marker-based assays, the expression level of a molecular marker reports a particular biological event. This approach allows to target biological pathways and perform compound screenings in model systems to identify compounds that interfere with specific developmental processes.