Does Antigen Size Matter?

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June 22, 2011

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The size used to develop antigens is a very important consideration. The longer the segment of amino acids, the more likely it will naturally conform to a native shape thereby being more likely to cause antibodies to be produced in the native conformation. Antibodies which recognize the natural shape of the targeted protein will more likely be a successful antibody in functional assays.

Drug DiscoveryImmunologyInformaticsMass Spectrometry

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