SARS-CoV-2 Omicron Variant



May 4, 2023

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  • Compared to previous variants, Omicron variant has a total of 60 mutations: 50 nonsynonymous mutations, 8 synonymous mutations, and 2 non-coding mutations. The variant has 32 mutations at the spike protein region, many of which have not been observed in other variants. The variant is characterized by 30 amino acids, three small deletions, and a small insertion in the spike protein compared to the original virus, wherein 15 is located in the receptor-binding domain. In addition, three mutations affect the Furin cleavage site, which adds SARS-CoV-2 infectivity.

    BiopharmaDrug DiscoveryImmunology

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