Delivery System Based on Liposome



May 4, 2023

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  • Liposomes, first described by British haematologist Dr Alec D Bangham FRS in 1961, are spherical vesicle having at least one lipid bilayer. These molecules have a head group and a tail group. The head is attracted to water, whereas the tail is made of a long hydrocarbon chain and is repelled by water. Liposomes often consist of phospholipids, especially phosphatidylcholine, and other lipids, such as egg phosphatidylethanolamine, as long as they are compatible with lipid bilayer structure. The primary types of liposomes are multilamellar vesicle with several lamellar phase lipid bilayers, small unilamellar liposome vesicle (SUV, with only one lipid bilayer), large unilamellar vesicle (LUV), and cochleate vesicle. Multivesicular liposomes are considered as the less desirable form in which one vesicle has one or more smaller vesicles. The liposomes can be used as a vehicle (delivery system) for the administration of nutrients and pharmaceutical drugs.

    BioengineeringDrug DiscoveryImmunology

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