Organoid Culture Made Easy With Hilary Sherman

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Teach Me in 10

It's easy to see why organoids have become popular over the years. These 3D cell cultures can self-organize into "mini-organs" capable of recapitulating their respective organ-specific functions. Organoids have been developed for several types of human organs, including the brain, breast, colon, liver, pancreas, stomach, esophagus, small intestine, ovary, uterus, fallopian tubes, prostate and retina. However, organoids are more complex compared to traditional 2D cultures and even 3D spheroids. Fortunately, products such as the Corning Matrigel® matrix – the most widely used and cited extracellular matrix (ECM) – can help streamline workflows for more efficient culturing, storing and handling. This Teach Me in 10 will cover best practices to consider for organoid work, as well as how to use Corning Matrigel matrix and other products to support organoid models in research.