Antibody based Cancer Therapies



March 30, 2021

Monoclonal antibodies are produced by identical immune cells that are clones of a specific parent cell. Monoclonal antibodies can only recognize the same antigen and epitope. Polyclonal antibodies are produced by different immune cells that have affinity for different epitopes of the same antigen. Therefore, monoclonal antibodies are much more specific and with less background noise than polyclonal antibodies. However, monoclonal antibodies are also usually more expensive to produce, less robust and are very sensitive to small changes in the antigen compared with polyclonal antibodies.

Cancer Research

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