Cytation Cell Imaging Multi-Mode Plate Readers: Ready for Any Assay



February 4, 2021

BioTek’s Cytation Cell Imaging Multi-Mode Readers are the most advanced microplate readers on the market, delivering performance, versatility and reliability in a unique, patented design. And now with Cytation C10 with confocal imaging you can do even more. Cytation combines automated digital upright and inverted widefield microscopy with multi-mode detection to capture both quantitative data and phenotypic information on a single platform. Cytation’s modularity and upgradability provides the ability to expand the system as your laboratory’s applications increase. Cytation is truly ready for any assay. Cytation’s inverted microscope has a 1.25x to 60x objective range enabling a wide range of applications from whole organism imaging to intracellular analysis, in brightfield, high contrast brightfield, color brightfield, phase contrast and fluorescence microscopy. The upright microscope has a 1x to 8x objective range expanding the scope of applications to Region of Interest or ROI identification and ELISpot assays. Cytation’s temperature control, gas control and shaking provide the ideal environment for kinetic live cell imaging. BioTek's Cytation and Gen5 software work together seamlessly to create a unique, user-friendly microscopy experience, automated imaging capture, processing, and powerful image analysis – all in a single, compact system. Gen5’s exceptional processing capabilities include z-stacking to facilitate 3D cell structure analysis - captured z-stacks are automatically z-projected with a single click. Z-projection enables a fully focused view of challenging biology such as 3D spheroids, tissues and other thick samples. Montage stitching in Gen5 automatically and precisely stitches multiple tiles in a montage into a single high resolution image for workflows including slide scanning and large sample imaging. Image analysis tools in Gen5 cover a very broad range of applications and are powerful and easy to use. Gen5 automatically identifies cell nuclei for rapid cell counting. Cytoplasm size, shape, intensity, and other morphological and phenotypical changes are also easily observed and characterized. Gen5’s unique spot count function allows in-depth analysis of intracellular objects, or spots, within a primary or secondary mask. Many other applications, including label-free cell counting, % confluence determination, subpopulation analysis, and signal translocation are efficiently and automatically analyzed with the powerful tools in Gen5. Cytation 1 - Digital microscopy and essential multi-mode microplate detection Cytation 5 - Powerful imaging & microscopy and advanced multi-mode detection Cytation 7 - Upright and inverted cell imaging plate reader, enabling a wide range of applications Cytation C10 - Spinning disk confocal microscopy with multimode detection With its modular inverted and upright microscopes and multi-mode detection in one unique, patented design, Cytation is the most advanced, versatile and reliable imaging reader on the market. Cited in more than 1650 scientific papers since its introduction in 2013, Cytation is truly Ready for any assay. Cytation line of instruments overview and comparison Cytation 1 Cell Imaging Multi-Mode Reader Cytation 5 Cell Imaging Multi-Mode Reader Cytation 7 Cell Imaging Multi-Mode Reader Cytation C10 Confocal Imaging Reader Gen5 Microplate Reader and Imager Software Gas controller for CO2 and O2 control Take3 Micro-Volume Plate BioStack Microplate Stacker BioSpa 8 Automated Incubator

AutomationCell CultureDrug DiscoveryImaging/Microscopy

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