You will hear from leaders in the field using the uncompromised scan speed, sensitivity and robustness of the timsTOF Pro mass spectrometer to elucidate protein-protein interaction networks. André Michaelis (Professor Matthias Mann Lab at MPI) will present TIMS and PASEF® technology and its application in successfully performing over 4150 pull-downs and the completion of more than 8300 LCMS measurements in less than 20 weeks for proteome-wide interaction studies in S. cerevisiae. Professor Peter Jackson (Stanford University) will present on how combining affinity purification mass-spectrometry (AP/MS) and shotgun proteomics with genetic interaction mapping reveals new proteins critical for KRAS-driven cancers.
Mass SpectrometryMolecular BiologyProteomics and Metabolomics