Bottom-up Proteomics and Top-down Proteomics

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July 1, 2021

Proteomics studies play an increasing role in the field of biology. The use of mass spectrometry (MS) in combination with a range of separation methods is the main principal methodology for proteomics. The two principal approaches to identifying and characterizing proteins using MS are the “bottom-up”, which analyze peptides by proteolytic digestion, and “top-down”, which analyze intact proteins. More at https://www.creative-proteomics.com/

Proteomics and Metabolomics

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