The introduction and synthesis route of small molecule kinase inhibitors approved by FDA in 2017



June 18, 2019

  • Share
  • A total of seven new small molecule kinase inhibitors have been approved by FDA in 2017. Protein kinases form a very large family of signaling proteins, with more than 500 encoded in the human genome. They have many diverse roles in cells and can be regulated in a variety of ways providing essential nodes in intracellular signaling pathways that act to define and/or integrate intracellular communication. A protein kinase is a kinase enzyme that modifies other proteins by chemically adding phosphate groups to them. Phosphorylation usually results in a functional change of the target protein by changing enzyme activity, cellular location, or association with other proteins. Protein kinases fall into two major categories, serine/threonine-specific protein kinases and tyrosine-specific protein kinases. Many researches proved that the protein kinases are the ideal drug targets. More at

    Drug Discovery

    Keep up to date with all your favourite videos and channels.

    Get personalised notifications on new releases and channel content by subscribing to the LabTube eNewsletter.