ADC antibody



February 16, 2019

A variety of methodologies in ADC antibody design and engineering introduce a series of specific and chemically versatile conjugation sites into the antibody sequences, including incorporating Cysteine residues into defined sites on an antibody to create thiol-engineered antibody (EnCys-mAb) and conjugate payload drugs onto those Cysteine residues via thiol-based chemistry.

Cancer ResearchDrug Discovery

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