Can I get UPLC or UHPLC performance on an HPLC system? | Trust your Science 10

793 views

|

August 25, 2018

Can I improve lab efficiency by purchasing modern columns, but using them on older HPLC equipment? Will using smaller particle columns on older systems get ultra performance? What about solid-core column materials, will using them increase efficiency? Liquid chromatography column technology has come a long way over the years. The once-traditional 4.6-mm internal diameter (i.d.) column packed with 5-µm particles are being replaced with smaller i.d. columns (2.1 mm) packed with smaller, sub-2-µm particles due to increased column efficiency. Claims have been made that you can obtain gains in efficiency by simply utilizing a high-efficiency column on your existing HPLC system. In this episode of Trust your Science, Kim and Jon take a look at using narrow bore, high-efficiency columns on HPLC, UHPLC, and UPLC systems and see what impact, if any, these systems have on efficiency.

ChromatographyMass Spectrometry

Keep up to date with all your favourite videos and channels.

Get personalised notifications on new releases and channel content by subscribing to the LabTube eNewsletter.