Solving of the Structure of Misfolded Tau in Pick's Disease

1,302 views

|

August 29, 2018

Dr Sjors Scheres, Group Leader at the MRC's Laboratory of Molecular Biology, UK, discusses his latest research solving the structure of misfolded tau in Pick's Disease (Frontotemporal Dementia, FTD). Using Cryo-EM the group solved the structure of the misfolded tau protein isolated from the brain of a patient that had died of FTD at the molecular level, approaching 3 Angstroms resolution. Sjors explains how Cryo-EM works, and how the group used it to make their findings. He also explains the impact these fundamental findings will have on the field and human health.

Imaging/MicroscopyMolecular BiologyNeuroscienceProteomics and Metabolomics

Keep up to date with all your favourite videos and channels.

Get personalised notifications on new releases and channel content by subscribing to the LabTube eNewsletter.