The Complete Guide to CAR-T Toxicity Monitoring and Treatment

Chimeric antigen receptor T-cell immunotherapy (CAR-T) allows modified T cells to have stronger and more durable targeted cytotoxicity against tumor cells by specifically recognizing tumor-associated antigens. In recent years, CAR T immunotherapy has been the most populous cancer immunotherapy in the world, which achieved great success and breakthrough. However, CAR-T has some specific side effects, such as Cytokine release syndrome (CRS), CAR-T cell-related encephalopathy (CRES), CAR-T-associated hemocyte Syndrome.