Using High-Throughput (HT) Methods to Accelerate Design of Experiments



March 13, 2017

"For more info, visit In this video, Dr Esteban Freydell describes a case study in high-throughput experimentation (HTE) using a design of experiments (DOE) methodology to study the mass recovery of a basic therapeutic protein (pI 9.2-9.5) using a hydrophobic cation exchange mixed-mode resin. BIo-Rad's Nuvia™ media are a family of best-in-class ion exchangers built with exceptionally high capacities and excellent purification capabilities, providing process developers with greater flexibility and higher productivity. Nuvia S is an ultra-high capacity, next-generation cation exchange media built on the industry-proven UNOsphere™ base matrix technology. Nuvia Q is an ultra-high capacity, next-generation anion exchange media that delivers high binding capacity across a range of pH and flow rates, providing a wide experimental design space for process developers."


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