The patented single-cell printing technology, developed by cytena, enables fully automated isolation of single cells into standard microwell plate formats. The instrument uses an inkjet-like principle featuring a disposable, one-way printing cartridge.
The cell sample is pipetted into the cartridge and an external actuator is used to eject droplets out of it. The integrated optical sensor allows for determination of cell number in each droplet. A fast shutter mechanism sorts the droplets containing exactly one single-cell into the substrate. Unwanted droplets are deflected into waste.