Behind the Science, ep. 6: Problem Child

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Waters Corporation

It’s time for a glycan therapy session where scientists discuss the “problem children” in the laboratory. Our Behind the Science host Jen Fournier gives scientists coping strategies – and tips and tricks – for difficult glycosylation studies. Topics raised on the therapy couch: problems characterizing the N-glycans of EPO with HILIC and QTof-MS, comparing low-abundant glycan species between an innovator and a biosimilar, and separation of high mannose species critical pairs.