Cardiac iPSCs for Drug Discovery

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SELECTBIO

Heart disease is the cause of morbidity and mortality in the industrialized world. While the use of human induced pluripotent stem cell (iPSCs) in regenerative medicine is a long-term goal. Recent technological advancement has enabled the generation of patient-specific and disease-specific human induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) in vitro. iPSC-CMs carry all the genetic information and therefore may be an ideal platform for elucidating disease modeling, drug screening, and cell therapy. Here I will discuss recent advances in this technology in the cardiovascular field.