IonWorks HT System

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Molecular Devices

IonWorks HT is a complete turnkey system that benefits drug discovery researchers by increasing throughput to up to 3,000 patches per day and drastically reducing hands-on time. The IonWorks HT system performs whole-cell patch clamping on multiple cells in parallel and greatly increases throughput over existing high-information content methods. The system quickly loads the wells and achieves multiple seals at a time. During processing, the system measures whole-cell current from multiple cells simultaneously using the multi-channel (48) voltage clamp amplifier. The system aspirates from standard 96- and 384-well microplate formats and dispenses reagents in parallel with a 12-channel pipettor. With the IonWorks HT system, it is easy to set up and run experiments. Typical experiments measure an entire plate in about 30 minutes translating into overall throughput of up to 3,000 patches per day.