Microbiology

Biotech Videos 

Over the last 10 years, Creative Biolabs has becoming a leader of recombinant antibody (rAb) discovery, engineering and manufacturing, providing high quality service to customers in academia andindustry fields all over the world. Now we focus on antibody discovery services for virology researches. Empowered by advanced phage and yeast display platform, hybridoma platform, B cell sorting platform and single B cell sequencing technology, we are dedicated to providing specific virology antibodies within agreed timelines.
https://viroantibody.creative-biolabs.com/viroantibody-discovery-services.htm

Anti Virus Biomolecular Discovery

Plant Cell Technology

This is a step-by-step guide on how to create tissue culture media using agar. If you have any questions, leave a comment below; we'd be happy to help!  Get 10%OFF the tissue culture products you need using my code: https://www.plantcelltechnology.com/?ref=FP10

WHAT IS PLANT PRESERVATIVE MIXTURE?
Plant Preservative Mixture (PPM), is a broad-spectrum biocide/fungicide for plant tissue culture. PPM™ is the ultimate solution to the never-ending struggle against microbial airborne, waterborne and endogenous contamination.
Plant Preservative Mixture (PPM™): http://bit.ly/3ZLhXES

WHAT IS AGAR? 
Agar is a polysaccharide complex obtained through bleaching and hot water extraction of agarocytes from the red alga Rhodophyceae. The typical usage rate of 6 - 12 g/L medium. Supreme agar offers greater clarity of plant culture media.
Supreme TC Grade Agar: http://bit.ly/3T4nZy3

ADVANTAGES AND DISADVANTAGES OF PLANT TISSUE CULTURE
Still, trying to determine if Tissue Culture is for you? Check out some of the most common advantages and disadvantages in our latest feature: https://bit.ly/3q2XZVb

We are Plant Cell Technology, a leading plant tissue culture industry organization since 1995. We develop, produce, and market innovative solutions for global plant tissue culture operations and hobbyists. Our well-researched, certified, and trusted products keep your cultures healthy and contaminate-free. 

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How To Make Tissue Culture Agar - Gelling Agent

FRITSCH Milling and Sizing

In this video we present our FRITSCH EASY GTM classic line gas pressure and temperature measuring system. Continuous measurement of gas pressure and temperature directly in the grinding bowl turns the planetary mills [url][link] https://www.fritsch-international.com/sample-preparation/milling/planetary-mills/details/product/pulverisette-54-classic-line/ [/link][name] PULVERISETTE 5  [/name][/url] and  [url][link] https://www.fritsch-international.com/sample-preparation/milling/planetary-mills/details/product/pulverisette-6-classic-line/ [/link][name] PULVERISETTE 6 [/name][/url]of the FRITSCH classic line into analytical measuring systems.

Detailed info about our MillControl Software: [url][link] https://www.fritsch-international.com/sample-preparation/milling/software-millcontrol-premium-line/ [/link][name]  FRITSCH SOFTWARE MillControl  [/name][/url]

Using the EASY GTM system with the FRITSCH Planetary Mills [i]classic line[/i]

Creative Enzymes

Enzymes are essential for the sustainable growth and development of any form of life on the planet and act as biocatalysts in a variety of metabolic and biochemical reactions. Enzymes have been used as food preservatives for a long time. Nowadays, enzymes enable various food industries to improve the quality and stability of products while improving production efficiency. The potential applications of enzymes in the food industry include auxiliary extraction of nutrient compounds and improvement of concentration, yield, stability, and effective recovery, etc. The growing demand for sustainable food has strengthened the power to develop microbial enzymes. https://www.creative-enzymes.com/cate/food-and-beverage-applications_108.html

Enzymes in Food Industry

Aging (Aging-US)

Aging-US published this trending review on April 20, 2023, in Volume 15, Issue 8, entitled, “How can we modulate aging through nutrition and physical exercise? An epigenetic approach" by researchers from Algarve Biomedical Center, Research Institute (ABC-RI), University of Algarve Campus Gambelas, Faro 8005-139, Portugal; Algarve Biomedical Center (ABC), University of Algarve Campus Gambelas, Faro 8005-139, Portugal; Faculty of Medicine and Biomedical Sciences (FMCB), University of Algarve Campus Gambelas, Faro 8005-139, Portugal; Department of Critical Care, William Osler Health System, Etobicoke, Ontario, Canada; Champalimaud Research Program, Champalimaud Centre for the Unknown, Lisbon, Portugal.

DOI - https://doi.org/10.18632/aging.204668

Corresponding author - Pedro Castelo-Branco - pjbranco@ualg.pt

Abstract

The World Health Organization predicts that by 2050, 2.1 billion people worldwide will be over 60 years old, a drastic increase from only 1 billion in 2019. Considering these numbers, strategies to ensure an extended “healthspan” or healthy longevity are urgently needed.

The present study approaches the promotion of healthspan from an epigenetic perspective. Epigenetic phenomena are modifiable in response to an individual’s environmental exposures, and therefore link an individual’s environment to their gene expression pattern. Epigenetic studies demonstrate that aging is associated with decondensation of the chromatin, leading to an altered heterochromatin structure, which promotes the accumulation of errors.

In this review, we describe how aging impacts epigenetics and how nutrition and physical exercise can positively impact the aging process, from an epigenetic point of view. Canonical histones are replaced by histone variants, concomitant with an increase in histone post-translational modifications. A slight increase in DNA methylation at promoters has been observed, which represses transcription of previously active genes, in parallel with global genome hypomethylation. Aging is also associated with deregulation of gene expression - usually provided by non-coding RNAs - leading to both the repression of previously transcribed genes and to the transcription of previously repressed genes.

Age-associated epigenetic events are less common in individuals with a healthy lifestyle, including balanced nutrition, caloric restriction and physical exercise. Healthy aging is associated with more tightly condensed chromatin, fewer PTMs and greater regulation by ncRNAs.

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https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.204668

Subscribe for free publication alerts from Aging - https://www.aging-us.com/subscribe-to-toc-alerts

Keywords - aging, epigenetics, nutrition, caloric restriction, physical exercise

About Aging-US

Launched in 2009, Aging-US publishes papers of general interest and biological significance in all fields of aging research and age-related diseases, including cancer—and now, with a special focus on COVID-19 vulnerability as an age-dependent syndrome. Topics in Aging-US go beyond traditional gerontology, including, but not limited to, cellular and molecular biology, human age-related diseases, pathology in model organisms, signal transduction pathways (e.g., p53, sirtuins, and PI-3K/AKT/mTOR, among others), and approaches to modulating these signaling pathways.

Please visit our website at https://www.Aging-US.com​​ and connect with us:

SoundCloud - https://soundcloud.com/Aging-Us
Facebook - https://www.facebook.com/AgingUS/
Twitter - https://twitter.com/AgingJrnl
Instagram - https://www.instagram.com/agingjrnl/
YouTube - https://www.youtube.com/@AgingJournal
LinkedIn - https://www.linkedin.com/company/aging/
Pinterest - https://www.pinterest.com/AgingUS/

Media Contact
18009220957
MEDIA@IMPACTJOURNALS.COM

How Can We Modulate Aging Through Nutrition, Physical Exercise? An Epigenetic Approach

Agricultural channel

As a biotechnology company, Lifeasible is specialized in agricultural science, offering a wide variety of agro-related services and products for environmental and energy solutions.

https://www.lifeasible.com/

Lifeasible

Aging-US published this research paper as the cover for Volume 15, Issue 7, entitled, "p21 facilitates chronic lung inflammation via epithelial and endothelial cells" by researchers from the Department of Molecular Cell Biology, The Weizmann Institute of Science, Rehovot 7610001, Israel; Department of Life Sciences Core Facilities, The Weizmann Institute of Science, Rehovot 7610001, Israel; Department of Veterinary Resources, The Weizmann Institute of Science, Rehovot 7610001, Israel; Department of Immunology, The Weizmann Institute of Science, Rehovot 7610001, Israel.

DOI - https://doi.org/10.18632/aging.204622

Corresponding author - Valery Krizhanovsky - valery.krizhanovsky@weizmann.ac.il

Abstract

Cellular senescence is a stable state of cell cycle arrest that regulates tissue integrity and protects the organism from tumorigenesis. However, the accumulation of senescent cells during aging contributes to age-related pathologies. One such pathology is chronic lung inflammation. p21 (CDKN1A) regulates cellular senescence via inhibition of cyclin-dependent kinases (CDKs). However, its role in chronic lung inflammation and functional impact on chronic lung disease, where senescent cells accumulate, is less understood. To elucidate the role of p21 in chronic lung inflammation, we subjected p21 knockout (p21-/-) mice to repetitive inhalations of lipopolysaccharide (LPS), an exposure that leads to chronic bronchitis and accumulation of senescent cells. p21 knockout led to a reduced presence of senescent cells, alleviated the pathological manifestations of chronic lung inflammation, and improved the fitness of the mice. The expression profiling of the lung cells revealed that resident epithelial and endothelial cells, but not immune cells, play a significant role in mediating the p21-dependent inflammatory response following chronic LPS exposure. Our results implicate p21 as a critical regulator of chronic bronchitis and a driver of chronic airway inflammation and lung destruction.

Sign up for free Altmetric alerts about this article - 
https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.204622

Subscribe for free publication alerts from Aging - https://www.aging-us.com/subscribe-to-toc-alerts

Keywords - aging, cellular senescence, chronic lung inflammation, p21 (CDKN1A)

About Aging-US

Launched in 2009, Aging-US publishes papers of general interest and biological significance in all fields of aging research and age-related diseases, including cancer—and now, with a special focus on COVID-19 vulnerability as an age-dependent syndrome. Topics in Aging-US go beyond traditional gerontology, including, but not limited to, cellular and molecular biology, human age-related diseases, pathology in model organisms, signal transduction pathways (e.g., p53, sirtuins, and PI-3K/AKT/mTOR, among others), and approaches to modulating these signaling pathways.

Please visit our website at https://www.Aging-US.com​​ and connect with us:

SoundCloud - https://soundcloud.com/Aging-Us
Facebook - https://www.facebook.com/AgingUS/
Twitter - https://twitter.com/AgingJrnl
Instagram - https://www.instagram.com/agingjrnl/
YouTube - https://www.youtube.com/@AgingJournal
LinkedIn - https://www.linkedin.com/company/aging/
Pinterest - https://www.pinterest.com/AgingUS/

Media Contact
18009220957
MEDIA@IMPACTJOURNALS.COM

p21 Facilitates Chronic Lung Inflammation via Epithelial and Endothelial Cells

Mutant library

Creative Biogene’s advanced technologies and highly experienced staffs are available to provide you a range of cDNA libraries construction service, including standard cDNA library, subtractive cDNA library, normalized cDNA library, full length cDNA library, yeast two-hybrid cDNA library and SSH cDNA library.

https://www.creative-biogene.com/Services/cDNA-Library-Construction-Service

cDNA Library Construction

Creative Biogene is a global leading agomir/ antagomir service provider for all passionate scientific researchers and our comprehensive synthesis service is supported by Cutting-Edge Chemical Synthesis Technology. Agomir/antagomir are members of a novel class of chemically engineered oligonucleotides.

https://www.creative-biogene.com/Services/MicroRNA-Agomir-Antagomir-Synthesis-Service.html

Microbiology

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