Immunology

Technology Networks

In this video, we speak with Dr Eric Yager, Associate Professor of Microbiology at the Center for Biopharmaceutical Education & Training to debunk common myths around new COVID-19 vaccines. 

COVID-19 Vaccine Myths – Debunked!

Teach Me in 10

When applying genetics to the study of COVID-19, scientists are learning a lot. Our DNA codes for proteins, some of which are required for SARS-CoV-2 to interact with and infect a host cell, others that are implicated in the downstream effects of viral infection, such as inflammatory responses. But how do scientists choose which genes to study? 

A new study by Dr Thomas Stoeger, a postdoc at North Western University, suggests there is a historical bias involved: scientists are studying human genes that have already been heavily investigated, independent of COVID-19. 
In this installment of Teach Me in 10, Stoeger expands on the key points of this study and the implications of bias in scientific research.

Full research publication: [url][link]https://elifesciences.org/articles/61981[/link][name]Meta-Research: COVID-19 research risks ignoring important host genes due to pre-established research patterns.[/name][/url]


Teach Me in 10 - Why COVID-19 Genetics Research May Be Biased With Dr Thomas Stoeger

Synthetic biology is a multidisciplinary research area that combines fields such as biology, engineering, chemistry, bioinformatics and systems biology. It is advancing at an impressive rate, largely due to the recent developments in genome engineering and genome editing in the post-genomic era. Synthetic biology influences various aspects of human life, such as modern medicine, drug development, agriculture, working to prevent climate change and even the chemistry of household products such as laundry detergent. In this installment of Teach Me in 10, we are delighted to welcome Dr Jake Wintermute, a systems biologist that works for INSERM France and teaches part of the Synthetic Biology Master's Program at the CRI in Paris. "My current research interests include the biology of aging, synthetic biology tools for drug discovery, and the human skin microbiome. I want to design, optimize and control microbial metabolism, usually with genetic techniques and usually with some application in mind, even it that application is far off," says Dr Wintermute. In this installment of Teach me in 10, Dr Wintermute provides a Synthetic Biology 101, teaching you everything that you need to know about this interesting area of science, in less than 10 minutes.

Teach Me in 10 – Why Synthetic Biology Will Eat Your Fields With Dr Jake Wintermute

In the last week, twin announcements from Pfizer and the Gamaleya Institute have suggested a vaccine for COVID-19 will probe effective at cutting infection rates. With only a minimal amount of analysis released, can we get excited about 2021 yet? 

Exploring the Coronavirus Pandemic: Can We Get Excited About A Vaccine Yet? 

How can plants be utilized in humanity's fight against COVID-19? That's the topic for this week's installment of Teach Me in 10, where we're joined by microbiologist [url][link]https://micro.cornell.edu/people/kathleen-hefferon/[/link][name]Dr Kathleen Hefferon[/name][/url] from Cornell University. When we think about plant-based medicines, often our minds jump to the past, where plants were used as therapies for thousands of years. But advances in modern technology are truly advancing plant-based therapeutics for applications in medicine today for a variety of diseases. In this installment of Teach Me in 10, Dr Hefferon talks us through the concept of plant-based therapeutics and focuses specifically on her research exploring plant-based vaccines for COVID-19.

Teach Me in 10 – How Can Plants Be Used To Fight COVID-19? With Dr Kathleen Hefferon

In this installment of Teach Me in 10, we are delighted to welcome William W. Li, MD. Dr Li is an internationally renowned physician, scientist and author of the New York Times bestseller “Eat to Beat Disease: The New Science of How Your Body Can Heal Itself.” His groundbreaking work has led to the development of more than 30 new medical treatments and impacts care for more than 70 diseases including cancer, diabetes, blindness, heart disease and obesity. His TED Talk, “Can We Eat to Starve Cancer?” has garnered more than 11 million views. Dr Li has appeared on Good Morning America, CNN, CNBC and the Dr. Oz Show, and he has been featured in USA Today, Time Magazine, The Atlantic and O Magazine. He is president and medical director of the Angiogenesis Foundation and is currently conducting research as part of the global fight against COVID-19. In this episode of Teach Me in 10 Dr Li discusses the relationship between food, health and disease and shares several examples of foods that have been shown to support the immune system. Imagine if we studied and tested foods in a similar way to medicines? How do the foods we eat interact with our body and how do our food choices influence our susceptibility to disease? Watch our lastest Teach Me in 10 video to find out more…

Teach Me in 10 – Food as Medicine With Dr William W. Li

Sekisui XenoTech

Presenter: Chris Bohl, Ph.D., Global Technical Support Manager This ADME 101 video provides an overview of different types of hepatocytes, their unique benefits, and when you use them for in vitro preclinical DMPK studies. This short, information-packed webinar features: - Why use hepatocytes instead of subcellular fractions - A comparison between: - primary and immortalized hepatocytes - fresh and cryopreserved primary hepatocytes - animal and human primary hepatocytes - Descriptions of the different hepatocyte formats available - A guide to selecting the right hepatocytes for your study - Recommendations for selecting and using those hepatocytes - An overview of tissue procurement and more... Download slides: https://www.xenotech.com/webinar-slides/sekisui-xenotech_hepatocytes-selection-adme-101.pdf Questions, comments and requests: https://www.xenotech.com/contact-us More information on our research services and test systems: https://www.xenotech.com Other previously aired webinars: https://www.xenotech.com/scientific-resources/webinar-series Upcoming webinar notifications: https://www.xenotech.com/newsletter-signup Request a webinar topic: https://www.xenotech.com/scientific-resources/upcoming-webinars About the presenter: Dr. Chris Bohl received his PhD from the School of Biological Sciences from the University of Nebraska – Lincoln and has been with SEKISUI XenoTech since 2014, first operating as a research scientist before becoming the Senior Manager of Technical Support for Products. Chris provides valuable guidance to scientists seeking to choose the correct test system, troubleshoot difficulties and much more.

ADME 101 Guide: Which Hepatocyte Test System Should I Use?

In a COVID-19 special of Teach Me in 10, we're joined by Clare Paterson, senior clinical R&D scientist at SomaLogic, who is currently working on using "omics" approaches to understand the biology of SARS-CoV-2. This work aims to identify biomarkers and predictive outcomes of COVID-19 infections. In this talk, Clare eloquently explains to us why, despite being incredibly important in understanding the biology of COVID-19, genetics is only part of the story. What can other "omics" approaches that are complementary to genomics also teach us? Learn more about some of the research studies Clare discusses and the application of omics in studying disease: https://jvi.asm.org/content/94/13/e00510-20, https://www.nejm.org/doi/full/10.1056/NEJMoa2020283, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7337378/, https://www.technologynetworks.com/proteomics/lists/clinical-omics-genomics-to-metabolomics-and-onwards-to-the-multi-omics-frontier-333715

Teach Me in 10 – Understanding COVID-19 Through "Omics" With Dr Clare Paterson

This instalment of Teach Me in 10 features Dr Charlotte Stadler, who began her research career as a PhD student within the Human Protein Atlas. Now, she is the Head of the Cell Profiling Facility at the Science for Life Laboratories where her focus lies in antibody-based imaging. In her Teach Me in 10 challenge, Stadler eloquently discusses the recent progress in antibody-based imaging, and how novel methods in this space are helping to facilitate advancements in proteomics research..

Stadler is a member of the EPIC-XS consortium and emphasizes that non-Swedish researchers can submit proposals for project support from the Cell Profiling Facility here.

You can also connect with Dr Stadler via LinkedIn.


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