Personalized Medicine

Sekisui XenoTech

Presented by SEKISUI XenoTech Technical Support Managers, Drs. Andrew G. Taylor and Chris Bohl Metabolic stability influences the oral bioavailability and plasma half-life of a compound. Metabolic stability assays measure intrinsic clearance and determine the extent to which a drug will be metabolized. This study can be conducted in a variety of test systems, which is why it may also be referred to as a hepatocyte stability study, microsomal stability study, etc. This quick overview video discusses: - Test systems for stability assays - Stability study endpoints - Example data in different species - Considerations for those wanting to conduct stability studies Download slides: https://www.xenotech.com/wp-content/uploads/2020/11/SEKISUI-XenoTech_Metabolic-Stability-ADME-101.pdf Questions, comments and requests: https://www.xenotech.com/contact/ More information on our research services and test systems: https://www.xenotech.com Other previously aired webinars: https://www.xenotech.com/access-adme-research-resources/resource-type/webinar/ Upcoming webinar notifications: https://www.xenotech.com/contact/newsletter-sign-up/ Request a webinar topic: https://www.xenotech.com/contact/webinar-seminar-request/ About the Presenters: Dr. Andrew G. Taylor received his Ph.D. from University of California San Diego. He joined SEKISUI XenoTech as a research scientist in 2017, serving as a Study Director in nonclinical drug interaction contract studies in compliance with Good Laboratory Practices (GLP), OECD Principles of GLP, &/or Japan MOHW GLP Standards and specializing in drug transport and drug metabolism studies. He became the Technical Support Manager for services in 2020 and provides valuable guidance to ensure research needs are being met. Dr. Chris Bohl received his PhD from the School of Biological Sciences from the University of Nebraska – Lincoln and has been with SEKISUI XenoTech since 2014, first operating as a research scientist before becoming the Senior Manager of Technical Support for Products. Chris provides valuable guidance to scientists seeking to choose the correct test system, troubleshoot difficulties and much more.

ADME 101: Drug Metabolism Studies – Metabolic Stability

Teach Me in 10

It's time for another installment of Teach Me in 10. This week, we're bringing you a two-part series with Dr Erik Procko from the University of Illinois at Urbana-Champaign. Dr Procko has been working on engineering a "decoy" receptor for SARS-CoV-2, the virus that has caused the COVID-19 global pandemic. In the first video of this two-part installment, Dr Procko explains exactly what a decoy receptor is, and how this strategy could be adopted in fighting SARS-CoV-2. If you'd like to learn more about Dr Procko's work, you can check out his [url][link]https://mcb.illinois.edu/faculty/profile/procko[/link][name]research page[/name][/url], read this [url][link]https://www.technologynetworks.com/biopharma/articles/can-we-fool-sars-cov-2-with-a-decoy-receptor-for-cell-entry-338385[/link][name]recent interview[/name][/url] with Technology Networks, or take a look at his latest publication in the journal [url][link]https://science.sciencemag.org/content/early/2020/08/03/science.abc0870[/link][name]Science[/name][/url].

Teach Me in 10 – Engineering a Decoy Receptor for SARS-CoV-2 With Dr Erik Procko, Part I 

In this installment of Teach Me in 10, we're joined by the New York Times best-selling author and former cardiac surgeon Dr Steven Gundry. Dr Gundry runs a clinic in America and is an active researcher who states that lectins – a type of protein produced by plants that are found in many foods – cause inflammation that is underlying many modern diseases. In this installment of Teach Me in 10, Dr Gundry takes us back to the beginning of his journey with lectin research and discuses some of his clinical experiences. You can visit Dr Gundry's [url][link]https://drgundry.com/[/link][name]website [/name][/url] to learn more. 

Teach Me in 10 – Not All Plants Want To Be Eaten With Dr Steven Gundry

Custom Videos from Technology Networks

Watch this video to learn how the Incucyte live-cell analysis system can be used to gain insights into metabolic changes in advanced cell models.

Measuring cancer cell metabolism

Therapeutic antibodies are one of the most successful immunotherapy strategies for the treatment of both hematologic cancers and solid tumors. This success is owed to technological advances that enable better specificity and safety.

This video highlights the innovative solutions that are addressing challenges in antibody-based discovery and development.

Next-generation Therapeutic Antibodies

The IncuCyte SX1 enables unparalleled access to live-cell insights. Automation at every step fast tracks your research from incubation to publication.

IncuCyte SX1

Technology Networks

In this video, Professor Andrew Pollard, Leader of the Oxford Vaccine Group, discusses the ongoing clinical trial of the coronavirus vaccine candidate ChAdOx1 nCoV-19.

Inside the UK's Coronavirus Vaccine Clinical Trial

z-microsystems

z-microsystems is a specialist for microfluidic consumables and Lab-on-a-Chip application, from development to high volume production of micro-structured plastic parts. Micro-tooling and micro injection moulding is our passion. We would like to be your inspiring partner from the idea to high-volume production. 

z-microsystems-microfluidic consumables

Beckman Coulter Life Sciences

Increase the reproducibility and throughput of your cell culture experiments by automating on Beckman Coulter Biomek liquid handlers. 

Personalized Medicine

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