Molecular Biology

Teach Me in 10

More than one in ten individuals suffer from side effects after receiving COVID-19 vaccinations, including tenderness, pain, warmth, itching or bruising at the injection site, and tiredness, chills, joint pain and nausea. These side effects are not a sign of the disease; COVID-19 vaccines cannot infect anyone with SARS-CoV-2. In which case, what is causing the side effects? Professor Martin Michaelis and Dr Mark Wass of University of Kent’s School of Biosciences explain in this week's installment of Teach Me in 10.

Why Do COVID-19 Vaccines Cause Side Effects?

Technology Networks

Several European countries have temporarily halted the administration of the Oxford/AstraZeneca COVID-19 vaccine, ChAdOx1, after reports of thrombotic events occurring in individuals that had previously received the vaccine. In this video interview, we speak with Dr Andrew Preston, reader in Microbial Pathogenesis at the University of Bath, to learn more about the situation and its potential implications for global vaccination strategies. Visit the Technology Networks COVID-19 vaccine [url][link]https://www.technologynetworks.com/biopharma/articles/keep-up-to-date-with-covid-19-vaccine-development-333016[/link][name]hub page[/name][/url]
to keep up to date with the latest vaccine news.

Oxford/AstraZeneca COVID-19 Vaccination Pause: What's the Story?

Mutant library

Gene reporter is a useful in vitro tool that facilitates live monitoring and tracking a cell type of interest. Lineage reporters are created using minimal lineage-specific promoter-driven reporter systems or via knock-in of the reporter into the endogenous promoter region. 

https://www.creative-biogene.com/support/genome-editing-generation-of-reporter-stem-cells.html

Generation of Reporter Stem Cells

Creative Biogene is a global leading agomir/ antagomir service provider for all passionate scientific researchers and our comprehensive synthesis service is supported by Cutting-Edge Chemical Synthesis Technology. Agomir/antagomir are members of a novel class of chemically engineered oligonucleotides.

https://www.creative-biogene.com/Services/MicroRNA-Agomir-Antagomir-Synthesis-Service.html

MicroRNA Agomir

Creative Biogene provides world-class packaging services for a variety of viral types using our QVirusTM platform. Creative Biogene's state-of-the-art facilities and highly experienced staff are available in order to assist in all areas of virus vector design and construction, as well as the generation of the virus in a quick turnaround. Our custom viral services are highlighted by a consistent high titer and large delivery viral counts.

https://www.creative-biogene.com/Services/Custom-Viral-Service

Custom Viral Service

CBD oil extraction one stop solution

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small scale oil extraction machine explosion proof system for safe operation, matched low temperature chillers optional, 15lbs-220lbs biomass/batch customize, contact info@toptionlab.com

small scale oil extraction machine

The most complicated instrument on planet earth resides inside of your skull – your brain.
Throughout your lifetime, your brain continuously revises its own wiring. This ability of the brain to change and adapt is referred to as neuroplasticity (neuro = neuron, plasticity = the malleability of the brain). Here to explain precisely what neuroplasticity is, how it happens and how we can harness it, is one of the world's leading minds in this area – Dr Michael Merzenich. For nearly five decades, Merzenich has been a leading pioneer in brain plasticity research. A professor emeritus neuroscientist at the University of California San Francisco, he is a recipient of one the world's top neuroscience prizes – the Kavli Prize – for his achievements in the field. In addition to contributing to over 232 scientific publications, Merzenich also writes books to communicate neuroscience research to lay audiences. His first book, Soft-Wired, offers advice on how to rejuvenate, remodel and reshape your brain. Merzenich is also the CSO and on the board of directors at Posit Science.

What is Neuroplasticity? With Dr Michael Merzenich

Stilla Technologies

Digital PCR (dPCR) technologies are powerful tools that can be adapted to a variety of specialized applications. This talk explores target multiplexing in qPCR and dPCR assays to maximize the potential of today’s PCR instruments.

Join us in this webinar as we discuss critical aspects for dye selection, address inter-assay dimer concerns, and compare singleplex with multiplex data to ensure assay compatibility. For more challenging targets, including multiplexing allelic discrimination assays, we will look closer at the advantages of IDT's Affinity Plus™ locked nucleic acid probes over conventional hydrolysis probes.

The second part of the webinar will focus on highly multiplexed dPCR assays using the new Stilla® naica® system for Crystal Digital PCR™. The naica® system is a complete digital PCR solution with flexible sample throughput and highly sensitive detection and quantification of target nucleic acids. The new Prism fluorescent scanner allows target detection in up to 6-color channels, enabling another exclusive dimension for multiplexed dPCR assays. We will also present data explaining SNP detection in liquid biopsy samples obtained using the naica dPCR instrument.

By Kimberley Gutierrez, Application Scientist Manager at
Stilla Technologies & Erik Wendlandt, Field Applications Scientist at Integrated DNA Technologies

Design and optimize high multiplexing digital PCR assays with the naica® system

This week at Teach Me in 10, we're joined by Professor Nicholas Pugh from Anglia Ruskin University. His research investigates the signaling mechanisms that are used by platelets during pathophysiological thrombus formation. He's particularly interested in the role of zinc as extracellular and intracellular signalling molecules. In this video, Professor Pugh brings us up close and personal with platelets. What are they? What are they essential for in human physiology? Why is it important that we study them? Watch this Teach Me in 10 to find out more.

Molecular Biology

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