Diagnostics

Arrayjet

Arrayjet manufacture the most advanced inkjet liquid handling for multiplex array-based diagnostics and POC devices.

An expert in bioprinting, Arrayjet install microarrayers and offer custom array printing services, worldwide.  The non-contact technology is up to 100-fold faster than pin-spotting or tip-dispensing systems and the Ultra Marathon series can print up to 1000 slides (or 200 microplates) in a single batch for commercial manufacture.

An optical QC system, the Iris, involves twin cameras that sit either side of the print head and work with intuitive software to evaluate printing in real-time.  Any missing spots are detected and reprinted automatically, and a full QC report is available at the end of each print run.

Arrayjet: Inkjet microarray printers in action

Biotech Videos 

Thyroid cancer (TC) remains the most common endocrine malignancy worldwide and its incidence and mortality has increased steadily over the last four decades.https://www.antibody-creativebiolabs.com/thyroid-cancer-overview-signaling-pathway.htm

Thyroid Cancer Overview

Handheld Raman Spectrometer

Handheld Raman Analyzer is very useful for verifying raw material. Finder edge 785 as a handheld Raman analyzer feature intuitive software and flexible adapter. It fully compliant FDA 21 CFR part 11. Welcome to consult.

HandHeld Raman Analyzer

Creative Biolabs

The severity and emergency of SARS-CoV-2 infection spurs an urgent need for antiviral drug and vaccine discovery. Creative Biolabs has spent considerable efforts to provide scientific support and comprehensive services to promote the success of this combat. 
https://sars-cov-2.creative-biolabs.com/novel-coronavirus-sars-cov2.htm

SARS-CoV-2 Introduction-Creative Biolabs

Wyss Institute for Biologically Inspired Engineering at Harvard University

Melanoma is a very severe cancer that is often diagnosed too late to save patients' lives, and most people do not regularly visit a dermatologist for skin exams. Early-stage identification of suspicious pigmented lesions (SPLs), ideally by primary care providers, could lead to improved melanoma prognosis. Researchers at the Wyss Institute and MIT have developed a deep learning algorithm that can differentiate SPLs from non-cancerous skin marks in wide-field images of patients' skin, such as those taken with a tablet or cellphone. This method could enable improved patient triaging, reduced medical costs, and earlier treatment of melanoma.

For more information, please visit: https://wyss.harvard.edu/news/identifying-ugly-ducklings-to-catch-skin-cancer-earlier/

Credit: Wyss Institute at Harvard University

Using deep learning to detect cancerous skin lesions

Understanding Animal Research

Factsheet on the forced swim test available here: https://www.understandinganimalresearch.org.uk/files/4216/0275/6025/FST_fact_sheet_-_final.pdf

The forced swim test is a behavioural test which assesses the efficacy of potential antidepressant treatments. It involves putting a rat or mouse into a small tank of water, from which it cannot escape. The water is heated to between 25 and 30 degrees Centigrade to ensure that the animals do not develop hypothermia, which would affect their welfare and the findings from the test. After a few minutes of swimming around and trying to climb out of the tank, the animal stops trying to escape and instead floats in the water, moving occasionally to keep floating.

The test typically lasts around five to six minutes, after which the animal is lifted out. It is not left in the water until the point of exhaustion. Rats and mice are naturally buoyant but if at any point during the test the animal were to look as though it were struggling to stay afloat, it would be taken out of the water.

The length of time that the animal was active and then floating (‘immobile’) in the water is recorded. Additional behaviours including swimming and climbing may also be recorded. Antidepressants make stressed animals move more than they would if they had not been given an antidepressant, so if the animal has been given an antidepressant treatment prior to the test it will spend more time swimming and less time floating. Animals that have not been given an antidepressant treatment (known as ‘controls’) or animals given a treatment that does not have antidepressant properties will spend less time swimming and more time floating.

By comparing the swimming and floating times of the dosed animals and the control animals, researchers can tell whether or not a potential new antidepressant is likely to be an effective treatment in depressed patients. If a potential treatment works in these animals, it can then go on to further stages of testing.

Forced Swim Test

BioFluidix

The BioSpot® workstation is the flexible tool for any low volume liquid handling task. The proprietary SiJet and PipeJet® non-contact dispensing technologies enable precise non-contact liquid handling in the picoliter to nanoliter range compatible with many types of substrates. Microliter volumes can accurately be dispensed with ValveJet dispensing channels. The BioSpot® offers a flexible stand-alone solution for automation of miniaturized liquid handling tasks like spotting, printing, coating and many others. Applications like lateral flow assay fabrication, preparation of microfluidic chips, spotting onto biosensors or coating of medical devices benefit strongly from the unique performance
and customizability of this workstation. Beside the low volume aspiration and tip wash functionality an integrated calibration unit implements unbeatbale accuracy. The SmartDrop system claibrates the dispensing performance automatically to you desired process parameters.

BioSpot workstation from BioFluidix for miniaturized liquid handling in life science, diagnostic production and pharma research

Instant NanoBiosensors Co., Ltd.

Join our Innovation Challenge today for free! All participants receive free analysis service and the chance to win additional service and collaboration opportunities worth $10,000 USD!

Free analysis includes KD, kd, ka, LOD, and LDR measurements for your biomarkers. 

Regardless if your project is big or small we hope you join. Be sure to apply through our website by March 31st, 2021.


Music: http://www.bensound.com/royalty-free-music

Instant NanoBiosensors' Innovation Challenge!

Teach Me in 10

This week at Teach Me in 10, we're joined by Professor Nicholas Pugh from Anglia Ruskin University. His research investigates the signaling mechanisms that are used by platelets during pathophysiological thrombus formation. He's particularly interested in the role of zinc as extracellular and intracellular signalling molecules. In this video, Professor Pugh brings us up close and personal with platelets. What are they? What are they essential for in human physiology? Why is it important that we study them? Watch this Teach Me in 10 to find out more.

Diagnostics

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