Diagnostics

Teach Me in 10

Harvesting your cells is an important step in maintaining healthy cultures.  Good technique will lead to a healthy single-cell suspension.  There are many harvesting options depending on the cell line and application.  In this video, we will discuss some tips and tricks for harvesting cells.

Techniques for Harvesting Adherent Cells with Hilary Sherman

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Learn more about Industrial Enzyme Production at Creative Enzymes at  https://www.creative-enzymes.com/service/industrial-enzyme-production_380.html

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Aging (Aging-US)

Aging (Aging-US) published this trending editorial in Volume 14, Issue 5, entitled, “Sex matters in Alzheimer’s disease?” by researchers Sheeja Navakkode, Toh Hean Ch’ng, and Sreedharan Sajikumar from the Department of Physiology, National University of Singapore.

DOI - https://doi.org/10.18632/aging.203950 (PDF Download)

Full text - https://www.aging-us.com/article/203950

Corresponding author - Sreedharan Sajikumar - phssks@nus.edu.sg

Keywords - Alzheimer's disease, LTP, behavioural tagging, sexual dimorphism, transcriptome profiling

About Aging-US

Launched in 2009, Aging-US publishes papers of general interest and biological significance in all fields of aging research and age-related diseases, including cancer—and now, with a special focus on COVID-19 vulnerability as an age-dependent syndrome. Topics in Aging-US go beyond traditional gerontology, including, but not limited to, cellular and molecular biology, human age-related diseases, pathology in model organisms, signal transduction pathways (e.g., p53, sirtuins, and PI-3K/AKT/mTOR, among others), and approaches to modulating these signaling pathways.

Please visit our website at http://www.Aging-US.com​​ and connect with us:

SoundCloud - https://soundcloud.com/Aging-Us
Facebook - https://www.facebook.com/AgingUS/
Twitter - https://twitter.com/AgingJrnl
Instagram - https://www.instagram.com/agingjrnl/
YouTube - https://www.youtube.com/agingus​
LinkedIn - https://www.linkedin.com/company/aging/
Pinterest - https://www.pinterest.com/AgingUS/

Aging-US is published by Impact Journals, LLC: http://www.ImpactJournals.com​​

Media Contact
18009220957
MEDIA@IMPACTJOURNALS.COM

Trending With Impact: Alzheimer’s Disease Differs Between Men and Women

Jointlab srl

Presentation of the wide range of Lauda thermostats.
Immersion thermostats; heating thermostats with tank; refrigerated thermostats; thermocryostats. Basic or advanced solutions for the laboratories of the future.

Check all the products, information and prices on www.jointlab.com, your Laboratory equipment center.
For Chillers and deep freezers: www.frigolab.eu/it, the biggest shop online about cold technology.

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FRITSCH Milling and Sizing

In this video you can see how you can effectively comminute pumpkin with liquid nitrogen with our Vibratory Micro Mill PULVERISETTE 0.
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Read info about our PULVERISETTE 0:  [url][link] https://www.fritsch-international.com/sample-preparation/milling/ball-mills/details/product/pulverisette-0/ [/link][name]Details Ball Mill PULVERISETTE 0 [/name][/url]

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Aging (Aging-US) published this trending research paper on February 2, 2022 in Volume 14, Issue 3, entitled, “Work-related stress and well-being in association with epigenetic age acceleration: A Northern Finland Birth Cohort 1966 Study” by researchers from the MRC Centre for Environment and Health, Department of Epidemiology and Biostatistics, Imperial College London, St Mary's Campus, London W2 1PG, United Kingdom; Laboratory of Biostatistics, Department of Biomedical Sciences, University of Sassari, Sassari 07100, Italy; Department of Epidemiology, Local Health Unit TO 3, Turin 10095, Italy; School of Educational Sciences and Psychology, University of Eastern Finland, Joensuu FI-80101, Finland; Division of Insurance Medicine, Karolinska Institutet, Stockholm 17177, Sweden; Center for Life Course Health Research, Faculty of Medicine, University of Oulu, Oulu 90014, Finland; Grantham Institute for Climate Change and School of Public Health, Imperial College London, London SW7 2AZ, United Kingdom; IIGM – Italian Institute for Genomic Medicine (IIGM), IRCCS Candiolo, Torino 10060, Italy.

DOI - https://doi.org/10.18632/aging.203872

Corresponding author - Anna Freni-Sterrantino - a.freni-sterrantino@imperial.ac.uk

Abstract

Recent evidence indicates consistent association of low socioeconomic status with epigenetic age acceleration, measured from DNA methylation. As work characteristics and job stressors are crucial components of socioeconomic status, we investigated their association with various measures of epigenetic age acceleration.

The study population included employed and unemployed men and women (n=604) from the Northern Finland Birth Cohort 1966. We investigated the association of job strain, effort-reward imbalance and work characteristics with five biomarkers of epigenetic aging (Hannum, Horvath, PhenoAge, GrimAge, and DunedinPoAm).

Our results indicate few significant associations between work stress indicators and epigenetic age acceleration, limited to a range of ±2 years, and smoking recording the highest effect on GrimAge age acceleration biomarker between current and no smokers (median difference 4.73 years (IQR 1.18, 8.41). PhenoAgeAA was associated with job strain active work (β=-1.301 95%CI -2.391, -0.212), slowing aging of less than 1.5 years, and working as white-collar slowed aging six months (GrimAgeAA β=-0.683, 95%CI -1.264, -0.102) when compared to blue collars. Association was found for working for more than 40 hours per week that increased the aging over 1.5 years, (HorvathAA β =2.058 95%CI 0.517,3.599, HannumAA β=1.567, 95%CI 0.415,2.719).

The pattern of associations was different between women and men and some of the estimated effects are inconsistent with current literature. Our results provide the first evidence of association of work conditions with epigenetic aging biomarkers. However, further epidemiological research is needed to fully understand how work-related stress affects epigenetic age acceleration in men and women in different societies.

Sign up for free Altmetric alerts about this article - https://oncotarget.altmetric.com/details/email_updates?id=10.18632%2Foncotarget.203872

Keywords - epigenetic age, job strain, effort-reward imbalance, work-related well-being, DNA methylation

About Aging-US

Launched in 2009, Aging-US publishes papers of general interest and biological significance in all fields of aging research and age-related diseases, including cancer—and now, with a special focus on COVID-19 vulnerability as an age-dependent syndrome. Topics in Aging-US go beyond traditional gerontology, including, but not limited to, cellular and molecular biology, human age-related diseases, pathology in model organisms, signal transduction pathways (e.g., p53, sirtuins, and PI-3K/AKT/mTOR, among others), and approaches to modulating these signaling pathways.

Please visit our website at http://www.Aging-US.com​​ and connect with us:

SoundCloud - https://soundcloud.com/Aging-Us
Facebook - https://www.facebook.com/AgingUS/
Twitter - https://twitter.com/AgingJrnl
Instagram - https://www.instagram.com/agingjrnl/
YouTube - https://www.youtube.com/agingus​
LinkedIn - https://www.linkedin.com/company/aging/
Pinterest - https://www.pinterest.com/AgingUS/

Aging-US is published by Impact Journals, LLC: http://www.ImpactJournals.com​​

Media Contact
18009220957
MEDIA@IMPACTJOURNALS.COM

Trending With Impact: Work-Related Stress and Biomarkers of Aging

If you had not heard of the polymerase chain reaction (PCR) technique prior to the COVID-19 pandemic, it’s likely that you are very familiar with it now. You may have even had a PCR test. So how does it work and how can it be used to detect infectious pathogens like SARS-CoV-2? For this Teach Me in 10 video, we’re joined by [url][link]https://www.acphs.edu/eric-yager-phd[/link][name]Dr. Eric Yager[/name][/url], director of the Pre-Pharmacy Program and associate professor at the Albany College of Pharmacy and Health Sciences. Dr. Yager provides a clear and concise 10-minute overview of how a PCR experiment is performed. 


Diagnostics

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