Genomics

Creative Biolabs

Genome editing is a set of methods used to change the DNA of a cell with single base-pair precision. It is a specific form of gene therapy, and the engineering of cells through genome editing has the potential to create a new class of medicines for the treatment of both genetic and nongenetic diseases. Today we will discuss the basic theories and clinic stages of genome editing methods, and Creative Biolabs' gene editing solutions for gene therapy development.
https://www.creative-biolabs.com/gene-therapy/gene-editing-for-gene-therapy.htm

Genome Editing Introduction

CD Genomics

· Highly integrated single-base resolution DNA methylation patterning; Providing insights into gene cell-fate commitment and reprogramming, as well as gene regulation; Identifying novel epigenetic markers and targets for disease· Unable to distinguish between 5mC and 5hmC
More information at https://www.cd-genomics.com/

5mC and 5hmC Sequencing Methods  and The Comparison

CD Genomics has been providing the accurate and affordable RNA-Seq (RNA sequencing) service for decades. We combine both Illumina (short reads) and PacBio (long reads) platforms to obtain the transcriptome that allows de novo assembly or re-sequencing for bacteria, plants, animals and humans. https://www.cd-genomics.com/RNA-Seq-Transcriptome.html

The Development and Workflow of RNA-seq -CD Genomics

CD genomics can provide microorganism quantification amplicon sequencing based on 16S external standard sequences to obtain absolute abundance data for species in the sample. The 16S amplicon library is constructed and sequenced by adding a synthetic sequence of known copy number to the sample DNA, and then a standard curve is drawn according to the number of amplicon reads and the absolute copy number of the external standard sequence. And finally the absolute copy number of the 16S rRNA gene of the corresponding species of the OTU representative sequence in the sample is calculated. More information at https://www.cd-genomics.com/absolute-quantitative-16s-18s-its-amplicon-sequencing.html

Bioinformatics Analysis of 16s rRNA Amplicon Sequencing Data - CD Genomics

Teach Me in 10

Science communicators serve an important role, bridging researchers with scientists in other fields, science professionals, industry experts and the general public. "How do I become a science writer?" is a common question that we get asked here at Technology Networks. That is why for this installment of Teach Me in 10, the guests are … well, us! We wanted to share stories of how we became science writers and communicators, highlighting some of the things that we have learned through our journeys and to offer some top tips and tricks. Further resources: [url][link]https://www.technologynetworks.com/tn/how-to-guides/how-to-become-a-science-writer-8-tips-to-guide-you-312458[/link][name]8 Tips on How To Become a Science Writer[/name][/url], [url][link]https://www.technologynetworks.com/tn/meet-the-team[/link][name]Meet the Technology Networks Team[/name][/url].

Becoming a Science Writer

The most complicated instrument on planet earth resides inside of your skull – your brain.
Throughout your lifetime, your brain continuously revises its own wiring. This ability of the brain to change and adapt is referred to as neuroplasticity (neuro = neuron, plasticity = the malleability of the brain). Here to explain precisely what neuroplasticity is, how it happens and how we can harness it, is one of the world's leading minds in this area – Dr Michael Merzenich. For nearly five decades, Merzenich has been a leading pioneer in brain plasticity research. A professor emeritus neuroscientist at the University of California San Francisco, he is a recipient of one the world's top neuroscience prizes – the Kavli Prize – for his achievements in the field. In addition to contributing to over 232 scientific publications, Merzenich also writes books to communicate neuroscience research to lay audiences. His first book, Soft-Wired, offers advice on how to rejuvenate, remodel and reshape your brain. Merzenich is also the CSO and on the board of directors at Posit Science.

What is Neuroplasticity? With Dr Michael Merzenich

V&P Scientific

The SpinVessel® won the New Product Award at the Society for Laboratory Automation and Screening (SLAS) trade show 2020. It is the first device of its kind to uniformly suspend particulates without the need for a stir bar. Aliquot while in motion. Cells can be kept in suspension for long periods of time and remain viable. Eight different volumes are currently available. Integrates easily onto a liquid handler.

Keep cells, magnetic beads, resins & more in suspension WITHOUT a stir bar!

Artel

In this short video Keith Albert, Senior Applications Specialist, gives an overview on how you can adjust pipetting variables to help optimize automated liquid handler (ALH) methods.  He will demonstrate this using the Artel MVS Multichannel Verification System as well as the Beckman Coulter Biomek automated liquid handler (ALH).

Adjusting Pipetting Variables to Optimize Methods

Stilla Technologies

Digital PCR (dPCR) technologies are powerful tools that can be adapted to a variety of specialized applications. This talk explores target multiplexing in qPCR and dPCR assays to maximize the potential of today’s PCR instruments.

Join us in this webinar as we discuss critical aspects for dye selection, address inter-assay dimer concerns, and compare singleplex with multiplex data to ensure assay compatibility. For more challenging targets, including multiplexing allelic discrimination assays, we will look closer at the advantages of IDT's Affinity Plus™ locked nucleic acid probes over conventional hydrolysis probes.

The second part of the webinar will focus on highly multiplexed dPCR assays using the new Stilla® naica® system for Crystal Digital PCR™. The naica® system is a complete digital PCR solution with flexible sample throughput and highly sensitive detection and quantification of target nucleic acids. The new Prism fluorescent scanner allows target detection in up to 6-color channels, enabling another exclusive dimension for multiplexed dPCR assays. We will also present data explaining SNP detection in liquid biopsy samples obtained using the naica dPCR instrument.

By Kimberley Gutierrez, Application Scientist Manager at
Stilla Technologies & Erik Wendlandt, Field Applications Scientist at Integrated DNA Technologies

Genomics

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