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Aging (Aging-US)

Oncoscience published this trending research perspective in Volume 9, 2022, entitled, "Altos Labs and the quest for immortality: but can we live longer right now?" by Dr. Mikhail V. Blagosklonny from Roswell Park Cancer Institute, Buffalo, NY. 

DOI - https://doi.org/10.18632/oncoscience.552

Corresponding author - Mikhail V. Blagosklonny - Blagosklonny@oncotarget.com, Blagosklonny@rapalogs.com

Abstract

Some visionaries prefer to dream of immortality rather than to actually live longer. Here I discuss how combining rapamycin with other modalities may let us live long enough to benefit from future discoveries in cellular reprogramming and what needs to be done at Altos Labs to make this happen.

Press release - https://aging-us.com/news_room/altos-labs-quest-for-immortality

Keywords - aging, longevity, lifespan, geroscience, rapalogs, gerostatics

About Oncoscience

Oncoscience's mission is to cover the rapidly growing field of cancer research. It’s aim is to focus on emergent topics not currently covered by other journals.

Launched in 2014, Oncoscience is a peer-reviewed, traditional-style, bi-monthly journal with free access. Oncoscience also has a special mission: freeing researchers in oncology from publication costs. It is free for both readers and authors.

Please visit our website at http://www.Oncoscience.us​ and connect with us:

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Oncoscience is published by Impact Journals, LLC: http://www.ImpactJournals.com​​

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Paper Spotlight: Altos Labs’ Quest for Immortality - Dr. Blagosklonny’s Perspective

Teach Me in 10

In this episode of Teach Me in 10, Lucy Lawrence is joined by the Global Product Manager of Applications and Flow Reagents at Bio-Rad Laboratories, Dr. Chris Brampton.

Chris will cover the basics of antibodies, the reasons why you need flow cytometry–specific antibodies and some basic best practices to achieve improved data and increase the likelihood of a successful outcome for flow cytometry experiments.

Top Tips for Antibodies and Flow Cytometry With Dr. Chris Brampton

Creative Enzymes

An enzyme is a biological catalyst and is almost always a protein. It speeds up the rate of a specific chemical reaction in the cell. The enzyme is not destroyed during the reaction and is used over and over. A cell contains thousands of different types of enzyme molecules, each specific to a particular chemical reaction.

 Enzymes play a key role in the metabolic activities of all organisms from human to microbial. The abnormality in metabolism leads to many metabolic disorders.

Studies have shown that many metabolic disorders are resulted from enzyme deficiency. Enzymes also have a wide range of applications in microbial biotechnology and the diagnosis process. They have been widely used in clinical examination as preferred markers in  disease states such as myocardial infarction, jaundice, pancreatitis, cancer, neurodegenerative disorders, etc. They provide insight into the disease process through the ability of diagnosis, prognosis, and assessment of response therapy.
Studies have shown that many metabolic disorders are resulted from enzyme deficiency. Enzymes also have a wide range of applications in microbial biotechnology and the diagnosis process. They have been widely used in clinical examination as preferred markers in  disease states such as myocardial infarction, jaundice, pancreatitis, cancer, neurodegenerative disorders, etc. They provide insight into the disease process through the ability of diagnosis, prognosis, and assessment of response therapy.
https://www.creative-enzymes.com/product/native-microorganism-nacetylneuraminic-acid-aldolase_778.html

Creative Enzymes: Featured  Enzyme  Products  for  Diagnostic  Use

An immobilized enzyme is an enzyme attached to an inert, insoluble material—such as calcium alginate. This can provide increased resistance to changes in conditions such as pH or temperature. It also lets enzymes be held in place throughout the reaction, following which they are easily separated from the products and may be used again - a far more efficient process and so is widely used in industry for enzyme catalysed reactions.
  https://www.creative-enzymes.com/service/enzyme-stabilization-by-immobilization_368.html

Creative Enzymes: Enzyme Immobilization

Creative Proteomics videos

Proteomics studies play an increasing role in the field of biology. The use of mass spectrometry (MS) in combination with a range of separation methods is the main principal methodology for proteomics. The two principal approaches to identifying and characterizing proteins using MS are the “bottom-up”, which analyze peptides by proteolytic digestion, and “top-down”, which analyze intact proteins.  https://www.creative-proteomics.com/resource/top-down-proteomics-vs-bottom-up-proteomics.htm

Bottom-up Proteomics and Top-down Proteomics at Creative Proteomics

eTheRNA Manufacturing, a specialist RNA process developer and manufacturing member of the Belgian eTheRNA group offers RNA manufacture and LNP formulation. eTheRNA’s COO and Senior Vice President of Manufacturing joins us for this instalment of Teach Me in 10 to provide you with an overview of RNA and LNP, what resources they provide for your needs and why they are one of the finest suppliers in this field.

Everything You've Always Wanted to Know About RNA Production and LNP Formulation, but Were Too Afraid to Ask with Bernard Sagaert

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The cannabis industry is expanding more rapidly than ever before. A similar trajectory is emerging within the psychedelics industry. Our latest Teach Me in 10 episode is a two-part collaboration with our sister site Analytical Cannabis, which examines the impact of these rapidly evolving industries and the next season of a growing podcast. 

Our guest today is Dr. Nigam B. Arora, founding partner at Marcu & Arora. His podcast "How to Launch an Industry" combines meaningful and fact-based conversations with a rare, insider’s viewpoint to explore the hottest topics from the world of cannabis and psychedelics science. 

In part two, Lucy and Nigam take a deep dive into the creativity behind each episode, including the guests, experts and artists that contribute to the show.

The Inside Scoop on Cannabis and Psychedelics From Dr. Nigam B. Arora – Part 2

The cannabis industry is expanding more rapidly than ever before. A similar trajectory is emerging within the psychedelics industry. Our latest Teach Me in 10 episode is a two-part collaboration with our sister site Analytical Cannabis, which examines the impact of these rapidly evolving industries and the next season of a growing podcast. 

Our guest today is Dr. Nigam B. Arora, founding partner at Marcu & Arora. His podcast "How to Launch an Industry" combines meaningful and fact-based conversations with a rare, insider’s viewpoint to explore the hottest topics from the world of cannabis and psychedelics science. 

In part one, Lucy and Nigam discuss the upcoming series, and whether the current excitement about the renewed interest in psychedelics is a help or a hindrance.

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