Creative Proteomics videos

SILAC-based quantitative proteomics (SILAQ) is an innovative technology used in high throughput quantitative analysis of large protein complexes, protein-protein and protein-small molecule interactions. https://www.creative-proteomics.com/Services/SILAC-based-proteomics-analysis.htm

SILAQ

Creative Proteomics has established a highly sensitive HPLC-MS/MS pipeline that can analyze N- and O-methylation in both eukaryotic and prokaryotic organisms. In addition, we have optimized our protocol, to enable more fast and sensitive site mapping service for methylation analysis.

https://www.creative-proteomics.com/services/Methylation.htm

Protein Methylation Analysis

Protein-protein interactions (PPIs) are the basis of the cellular structure and functions. It has been estimated that more than 80% of proteins do not operate alone but in complexes. The analysis of PPIs is able to help us understand cellular organization, process, and functions. PPIs analysis may discovery unique and unforeseen functional roles for well-known proteins. And it can discover previously unknown proteins by association knowns proteins. https://www.creative-proteomics.com/

PPI Methods

Edman degradation, which was developed by Pehr Edman, is a method to sequence amino acids in a peptide. It is the Cyclic degradation of peptides based on the reaction of phenylisothiocyanate with the free amino group of the N-terminal residue.  More at https://www.creative-proteomics.com/

Protein Sequencing – Edman Degradation

At Creative Proteomics, we can provide de novo peptides or protein service. Equipped with state-of-the-art technologies such as high-performance liquid chromatograph coupled to tandem mass spectrometry (LC-MS/MS) and advanced computational algorithms, we can offer accurate and fast de novo peptide/protein sequencing service customized to your needs.
https://www.creative-proteomics.com/

Introduction to Novo peptide sequencing

Shotgun proteomics refers to the use of bottom-up proteomics techniques to study the whole proteins in a complex mixture, such as serum, urine, and cell lysates, etc. It utilizes the technology of high performance liquid chromatography (HPLC) in combination with mass spectrometry (MS) technology. The most distinctive feature of shotgun proteomics is that it enables identification and comparative quantification of a wide range of proteins at the same time with minimal protein separation needed.  More information can be found at https://www.creative-proteomics.com/services/shotgun-protein-identification.htm

Creative Proteomics videos

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