Mutant library

CRISPR (Clustered Regulatory Interspaced Short Palindromic Repeats)/Cas9 systems is a newly developed yet the most popular method for genome editing. It has been widely used in current biology, functional genome screening, cell-based human hereditary disease modeling, epigenomic studies and visualization of cellular processes.

https://www.creative-biogene.com/Services/Stable-cell-line-generation/Custom-Genome-Editing-Cell-Lines.html

Stable Knockout Cell Line Generation

Oncolytic viruses (OVs) are a class of viruses that can selectively replicate in and lyse cancer cells, and subsequent spread with a tumor while not causing damage to normal cells. They have tremendous therapeutic potential to target and kill cancerous cell. Oncolytic virotherapy is an innovative treatment modality which uses replication competent viruses to destroy malignant cancers.

https://www.creative-biogene.com/Services/Custom-Viral-Service/Oncolytic-Virus-service.html

Oncolytic Virotherapy

Baculoviruses are arthropod-specific viruses containing large double-stranded circular DNA genomes of 80,000–180,000 bp. In recent years, they have been utilized for producing complex eukaryotic proteins in insect cell cultures. 

https://www.creative-biogene.com/services/Custom-Viral-Service/baculovirus-service.html

Baculovirus-Efficient Tool for Protein Expression

With the progress in gene-editing methods, one or more reporters can be engineered in the same pluripotent stem cell line and can provide visual cues for the progression from stem cell to progenitor to highly functional mature cell types.

https://www.creative-biogene.com/support/genome-editing-generation-of-reporter-stem-cells.html

Reporter Stem Cells Generation

Oncolytic viruses (OVs) are a class of viruses that can selectively replicate in and lyse cancer cells, and subsequent spread with a tumor while not causing damage to normal cells. Besides the direct oncolytic activity, OVs are also effective in stimulating the body immune responses which can further help recogonize, control or destroy cancer cells. Through the combination of the tumor-specific cell lysis and immune stimulation, OVs act their antitumor activities in situ.

https://www.creative-biogene.com/products/oncolytic-virus.html

Oncolytic Virus

Viral vectors have been widely used as gene delivery vehicles. Compared to the conventional transfection methods, transduction usually results in much higher gene delivery efficiency, sometimes almost 100%. These are especially useful for gene delivery into primary cells or stem cells which is recalcitrant to conventional transfection methodologies.

https://qvirus.creative-biogene.com/

Mutant library

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