Lonza

Do you wish to improve your drug discovery experimental setup? Ever wonder how to improve on cell line data. Explore your options with primary cells from multiple organs of the human body. Make the right choices for drug discovery. Learn more….

Human Body and Media Solutions

Watch this video to learn how to successfully thaw and plate primary hepatocytes from the experts at Lonza. Not only will you understand the basics of handling your cryopreserved primary hepatocytes, you will also glean tips and tricks to truly maximize your final cell count.
Read the Thawing and Plating Protocol: 
https://bioscience.lonza.com/lonza_bs/US/en/download/product/asset/29887

Learn how Lonza can support your liver research applications: 
https://bioscience.lonza.com/liver-studies-for-adme-tox-studies

Cryopreserved primary hepatocytes products from Lonza: 
https://bioscience.lonza.com/Catalogue/Products/ADME-and-Toxicology/c/5?q=%3A%3A%3A%3Alonza-sort%3A%3A%3A%3Alon_cl_PrimaryCellType%3A%3A%3A%3AHepatocytes


#ADME #Toxicology #Drugmetabolism #pharmacokinetic #DrugDiscovery #DrugDrugInteraction #hepatocytes #primarycells #Lonza

How to Thaw and Plate Primary Hepatocytes | Video Protocol

Watch our expert, Maureen Bunger, PhD, explain how our patented manufacturing process ensures that the DonorPlex™ Hepatocytes exhibit improved phenotype reproducibility. Additionally, we have a proprietary algorithm that predicts yield, viability and functional phenotype prior to manufacture which ensures individual customer specifications are met.

Learn more about DonorPlex™ Pooled Donor Human Hepatocytes:
https://bioscience.lonza.com/pooled-human-donor-hepatocytes

Learn how Lonza can support your liver research applications:
https://bioscience.lonza.com/liver-studies-for-adme-tox-studies

DonorPlex™ Pooled Donor Human Hepatocytes products from Lonza:
https://bioscience.lonza.com/search/?text=donorplex


#ADME #Toxicology #Drugmetabolism #pharmacokinetic #DrugDiscovery #hepatocytes #primarycells #FDA #Lonza #DrugDrugInteraction #DDI

DonorPlex™ Pooled Donor Human Hepatocytes Enable the Next Level of Reliability | Lonza

Advance your in vitro drug interaction studies to the next level! Watch this video to learn how our Interaction Qualified primary hepatocytes can increase your confidence in your DDI and metabolism studies.

Learn more about Interaction Qualified Primary Hepatocytes: https://bioscience.lonza.com/lonza_bs/US/en/interaction-qualified-hepatocytes


Learn how Lonza can support your liver research applications: https://bioscience.lonza.com/liver-studies-for-adme-tox-studies

Cryopreserved primary hepatocytes products from Lonza: https://bioscience.lonza.com/Catalogue/Products/ADME-and-Toxicology/c/5?q=%3A%3A%3A%3Alonza-sort%3A%3A%3A%3Alon_cl_PrimaryCellType%3A%3A%3A%3AHepatocytes
#ADME #Toxicology #Drugmetabolism #pharmacokinetic #DrugDiscovery #hepatocytes #primarycells #FDA #Lonza #DrugDrugInteraction #DDI

Interaction Qualified Primary Hepatocytes | Lonza Product Overview

In this online symposium Drs. Jessica Hartman and Martin Phillips present 2D and 3D models being developed by ScitoVation for assessing hepatotoxicity. By combining Lonza’s primary hepatocytes and liver non-parenchymal cells in 2D or 3D models, the viability, phenotypic behavior, and response of cells to chemicals is enhanced.

This webcast explores how scientists can improve the physiological relevance of their in vitro liver models, while ensuring the complexity of cultures is kept to a minimum, saving laboratories both time and money.

Topics covered include:

- Hepatocytes as a metabolically active, in vitro test system
- Comparison of existing technologies
- Alginate encapsulation for testing slowly-cleared chemicals
- Development of 2D and 3D organotypic rat liver models

Designed for Purpose - Complex Liver Cell Cultures for Improving In Vitro Hepatotoxicity Testing

Lonza’s Nucleofector™ Technology is an improved electroporation technology that can help you achieve high transfection efficiency in primary cells, stem cells and hard to transfect cell lines. This video shows how to use the X Unit of the 4D-Nucleofector™ System with its two different vessel types: The 100 microliter cuvettes for high cell numbers at low throughput (e.g. for biochemical applications or Western Blots) and the 20 microliter 16-well strips for low cell numbers at medium throughput (e.g. reporter gene assays, RNAi, CRISPR). Nucleofection conditions are transferable between both vessel types offering maximum flexibility and convenience.<br/><br/>Learn more about the 4D-Nucleofector™ System at <a href="http://www.lonza.com/4d" target="_blank">www.lonza.com/4d</a>

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