Cell Signaling Technology (CST)

Neal Rosen, M.D., Ph.D., from Memorial Sloan-Kettering Cancer Center discusses the biologic and therapeutic implications of oncoprotein-activated feedback 

Oncoprotein-activated feedback--biologic and therapeutic implications

A tutorial designed to give users a general overview of PhosphoSitePlus® and how it can be used effectively in your research.

web. http://www.phosphosite.org/

PhosphoSitePlus® Training Tutorial

Stimulation of membrane receptors by growth factors or cytokines results in signal transduction leading to the activation of the kinase Akt,. Active Akt then can activate (phosphorylate) a large number of downstream proteins (substrates) that can be grouped by their effects on protein synthesis, survival, proliferation, glucose metabolism, neuroscience and other cellular effects. This presentation discusses the details of upstream signaling involved in Akt activation. 

Visit http://www.cellsignal.com to see antibodies for the study of Akt Signaling.

PI3K - Akt Upstream Signaling from Cell Signaling Technology, Inc.

The predominant signaling pathways involved in human embryonic stem cell (ESC) pluripotency are TGF-β, FGF and Wnt signaling pathways. This video describes how these pathways lead to the activation of 3 key transcription factors, which activate the transcription of ESC specific genes.

Visit http://www.cellsignal.com to see antibodies directed against stem cell and lineage markers.

Pluripotency at the Molecular Level from Cell Signaling Technology Inc

3D rendered signal transduction animation featuring protein secretion and vesicle trafficking. This short video showcases secreted protein production from mRNA translation to exocytosis.

Protein Secretion and Vesicle Trafficking

Forest M. White, Ph.D., Associate Professor of Biological Engineering of the Koch Institute at MIT discussed his work using quantitative proteomics to analyze the systemic effect of genetic mutation on phenotype

Cell Signaling Technology (CST)

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