Chromatography & Mass Spectrometry Solutions

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Welcome to Charlie Chats:  Short Video Interviews

The investigations of the Isotope Hunter with Isotope Fingerprints

Hear how Janssen Pharmaceutica uses the Thermo Scientific Vanquish Duo UHPLC system to drastically reduce their process time from 3 days to one afternoon by employing an automatized LC-MS workflow (from sample prep to data analysis) for biopharmaceuticals characterization.

Janssen works faster with an automated LC-MS including Thermo Scientific Vanquish Duo UHPLC system

Educational video about extractables & leachable analysis, challenges & Thermo Scientific’s differentiated solutions to increase sample throughput, streamline workflows, increase confidence in results.

Extractables & Leachables: Challenges and Solutions

Extractables & Leachables: Overview

Learn more about Thermo Scientific Vanquish Flex UHPLC systems and what they can do for you. The biocompatible Vanquish Flex UHPLC system brings exceptional analytical precision, detector sensitivity, and operational simplicity to enable unprecedented robustness and flexibility.

Thermo Scientific Vanquish Flex UHPLC System: Complete Flexibility

An LC-HRAM-MS method with Thermo Scientific™ TurboFlow™ online SPE was developed and validated for the quantitation of immunosuppressants. Online SPE efficiently extracts analytes while removing other components in a crude supernatant, significantly simplifying sample preparation. The use of full-scan data-dependent MS2 acquisition allows for high-resolution selected-ion monitoring quantitation of the analytes, confirming the analytes using MS2 fragmentation, as well as monitoring the signal intensities of major immunosuppressant metabolites.

A Therapeutic Drug Monitoring Assay of Immunosuppressants using TurboFlow LC and High-Resolution Mass Spectrometry

Detect an ever-increasing number of substances at ever-decreasing concentrations. The Thermo Scientific™ Tox Explorer™ Collection helps the world’s toxicology community in forensics, clinical research, employee drug testing, and sports anti-doping navigate with ease to solve complex analytical challenges and increase productivity. Tox Explorer Collection is an all-in-one toxicology solution. Incorporating the TSQ Quantis Plus mass spectrometer for drugs of abuse testing enables sensitive and reproducible analytical measurement needed for confirmation for compounds covering a range of compound classes and polarities.

Chromatography & Mass Spectrometry Solutions

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