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rd1 mice receiving AAV2/5-HDAC4 injections perform similarly to the wild type CD1 mice on the open field test. They tend to stay in the dark chamber and try to avoid staying in the brightly lit chamber. They show hesitation in entering the brightly lit chamber from the dark chamber. 

Mice receiving AAV2/5-HDAC4 injection on the Open Field Test

Mice receiving AAV2/5-GFP injections don't show preference in staying in either the dark or the brightly lit chamber. They move constantly between the two chambers and don't show any hesitation to enter the brightly lit chamber.

rd1 mice receiving AAV2/5-GFP injection on the Open Field Test

Wild type animals tend to stay in the dark chamber and try to avoid staying in the brightly lit chamber. They show hesitance in entering the brightly lit chamber from the their preferred dark chamber. 

age-matched wild type CD1 mice on Open Field Test

An easy setup for the open field test with a dark connected to a brightly lit chamber that allows test animals to go freely between the two chambers.

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