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BioTek’s Cytation Cell Imaging Multi-Mode Readers are the most advanced microplate readers on the market, delivering performance, versatility and reliability in a unique, patented design. And now with Cytation C10 with confocal imaging you can do even more. Cytation combines automated digital upright and inverted widefield microscopy with multi-mode detection to capture both quantitative data and phenotypic information on a single platform. Cytation’s modularity and upgradability provides the ability to expand the system as your laboratory’s applications increase. Cytation is truly ready for any assay.

Cytation’s inverted microscope has a 1.25x to 60x objective range enabling a wide range of applications from whole organism imaging to intracellular analysis, in brightfield, high contrast brightfield, color brightfield, phase contrast and fluorescence microscopy. The upright microscope has a 1x to 8x objective range expanding the scope of applications to Region of Interest or ROI identification and ELISpot assays. Cytation’s temperature control, gas control and shaking provide the ideal environment for kinetic live cell imaging.

BioTek's Cytation and Gen5 software work together seamlessly to create a unique, user-friendly microscopy experience, automated imaging capture, processing, and powerful image analysis – all in a single, compact system.

Gen5’s exceptional processing capabilities include z-stacking to facilitate 3D cell structure analysis - captured z-stacks are automatically z-projected with a single click. Z-projection enables a fully focused view of challenging biology such as 3D spheroids, tissues and other thick samples. Montage stitching in Gen5 automatically and precisely stitches multiple tiles in a montage into a single high resolution image for workflows including slide scanning and large sample imaging.

Image analysis tools in Gen5 cover a very broad range of applications and are powerful and easy to use. Gen5 automatically identifies cell nuclei for rapid cell counting. Cytoplasm size, shape, intensity, and other morphological and phenotypical changes are also easily observed and characterized. Gen5’s unique spot count function allows in-depth analysis of intracellular objects, or spots, within a primary or secondary mask. Many other applications, including label-free cell counting, % confluence determination, subpopulation analysis, and signal translocation are efficiently and automatically analyzed with the powerful tools in Gen5.

Cytation 1 - Digital microscopy and essential multi-mode microplate detection
Cytation 5 - Powerful imaging & microscopy and advanced multi-mode detection
Cytation 7 - Upright and inverted cell imaging plate reader, enabling a wide range of applications
Cytation C10 - Spinning disk confocal microscopy with multimode detection

With its modular inverted and upright microscopes and multi-mode detection in one unique, patented design, Cytation is the most advanced, versatile and reliable imaging reader on the market. Cited in more than 1650 scientific papers since its introduction in 2013, Cytation is truly Ready for any assay.

 
Cytation line of instruments overview and comparison
https://www.biotek.com/cytation

Cytation 1 Cell Imaging Multi-Mode Reader
https://www.biotek.com/products/imaging-microscopy-cell-imaging-multi-mode-readers/cytation-1-cell-imaging-multi-mode-reader/

Cytation 5 Cell Imaging Multi-Mode Reader
https://www.biotek.com/products/imaging-microscopy-cell-imaging-multi-mode-readers/cytation-5-cell-imaging-multi-mode-reader/

Cytation 7 Cell Imaging Multi-Mode Reader
https://www.biotek.com/products/cell-imaging-microscopy-cell-imaging-multi-mode-readers/cytation-7/

Cytation C10 Confocal Imaging Reader
https://www.biotek.com/products/cell-imaging-microscopy-confocal-imaging-reader/cytation-c10/

Gen5 Microplate Reader and Imager Software
https://www.biotek.com/products/software-robotics-software/gen5-software-features-for-imaging-microscopy/

Gas controller for CO2 and O2 control
https://www.biotek.com/products/accessories/co2-only-gas-controller-for-synergy-neo2/

Take3 Micro-Volume Plate
https://www.biotek.com/products/accessories/take3-micro-volume-plate/

BioStack Microplate Stacker
https://www.biotek.com/products/software-robotics-robotics/biostack-microplate-stacker/

BioSpa 8 Automated Incubator
https://www.biotek.com/products/software-robotics-robotics/biospa-8-automated-incubator/

Cytation Cell Imaging Multi-Mode Plate Readers: Ready for Any Assay

Cytation™ C10 Confocal Imaging Reader combines automated digital confocal and widefield microscopy with conventional multi-mode microplate reading in a unique, patented design.   The spinning disk confocal module provides exquisite resolution and optical sectioning capabilities in a wide variety of sample types.  High quality components are used for excellent image quality, at a lower price than similar systems.  Cytation C10 also includes widefield fluorescence, brightfield and phase contrast optics. Its variable bandwidth monochromator-based plate reading provides fluorophore specificity and sensitivity.  Environmental controls enable live cell assays, and Gen5™ software is designed to make sample detection and image capture effortless.

Products:
Cytation C10 Confocal Imaging Reader
https://www.biotek.com/cytationC10​

Cytation Automated Microscopes & Multi-Mode Plate Readers
https://www.biotek.com/products/cytation.html

Gen5 Software
https://www.biotek.com/products/software-robotics-software/gen5-microplate-reader-and-imager-software/

BioStack Microplate Stacker
https://www.biotek.com/products/software-robotics-robotics/biostack-microplate-stacker/

BioTek Imager & Microplate Reader Technologies
https://www.biotek.com/products/imaging-detection-technologies.html

Cytation C10 Confocal Imaging Reader

The BenchCel Microplate Handler is a fast and simple benchtop microplate storage and handling system that automates common, high-throughput lab workflows. The BenchCel features a high-speed robot, and its modular design provides the flexibility and scalability required to meet the needs of the most diverse laboratory applications.

BenchCel can be interfaced with a range of BioTek instruments, including the EL406 and the MultiFlo FX Washer Dispensers to automate liquid handling operations. Synergy Neo2 and Epoch2 Microplate Readers enable detection workflows, while the Cytation 5 Imaging Reader allows the automation of detection and microscopy processes. Because the BenchCel accommodates a broad range of labware, including deep well microplates, many applications can be automated with a BenchCel integration.

The variety of configurations allows automating common workflows such as:
● ELISA
● Add & read assays
● Cell Fix, Stain & Image Protocols
● And many others

VWorks software offers an intuitive graphical interface and dynamic scheduling capabilities. Users can create and run protocols, forms and monitor progress of their workflows from VWorks.

Related links:

BenchCel Microplate Handler https://www.biotek.com/benchcel

BioTek Robotics https://www.biotek.com/products/robotics-category

BioTek Multi-Mode Washer Dispensers
https://www.biotek.com/products/liquid-handling
https://www.biotek.com/el406
https://www.biotek.com/multiflofx

BioTek Microplate Readers
https://www.biotek.com/cytation5
https://www.biotek.com/neo2
https://www.biotek.com/epoch2

Agilent VWorks Automation Control Software
www.agilent.com/en/products/software-informatics/automation-solutions/vworks-automation-control-software

BenchCel Automated Microplate Handler

The Cell Count & Viability App is designed to automate hemocytometer based counting of suspended mammalian cells using phase contrast imaging with BioTek imagers. Manual cell counting is tedious and prone to errors. Automating the cell counting process removes human error and increases data quality. The Cell Count & Viability App's intuitive interface is simple to use and requires no training. The app can analyze up to eight samples per run and automatically calculates the live/dead cell percentage. It also includes a calculator to determine how much sample and media are required to reach a desired cell concentration to facilitate downstream applications.

This software app is part of BioTek’s Cell Count & Viability Starter Kit, which includes software, 50 disposable counting slides, a slide holder for up to 4 counting slides, and a 1.5mL vial of 0.4% Trypan blue. Click below to learn more.

 
https://www.biotek.com/cellcountandviability
https://www.biotek.com/products/software-software-apps/cell-count-viability-app/
https://www.biotek.com/products/imaging-microscopy
https://www.biotek.com/applications/cell-counting.html

How to Use BioTek's Cell Count & Viability Application

This video explores BioTek’s unique structure and culture. BioTek is vertically integrated allowing us to control our entire value stream from the conceptualization of a new product, through its research and development, manufacturing, and ultimately the sales, service and support of that product. BioTek’s collaborative culture fosters open, honest communication resulting in dynamic feedback loops within the company and between BioTek and its customers. This combination of tight vertical integration and effective communication has enabled BioTek to thrive and innovate, making cutting edge research tools that are improving the quality of life for people in the world.

Visit https://www.biotek.com/about/ to learn more about BioTek.

BioTek: Passion and Innovation

This is a tutorial video about optimizing your microplate-based scratch migration assays by effectively washing samples after scratches have been formed. Post-scratch washing is an important step in the wound healing assay protocol, whether you are generating your scratches manually, or using the fully automated BioTek AutoScratch Wound Making Tool to efficiently create uniform scratches in either 24- or 96-well microplates. When done correctly, manual washing of scratches will reduce problematic cellular debris from the microplate wells and produce cleaner results compared to omitting this step. However, manual washing is a time consuming process that can produce variable results. For a more reliable and convenient solution, BioTek has developed a fully automated method to quickly and effectively wash either a 24- or 96-well microplate using the MultiFlo FX Multi-Mode Dispenser. With this approach, 3 wash cycles are performed in a fraction of the time required for manual washing, using aspiration and dispense steps optimized for the scratch assay. Products: Scratch Assay Starter Kit https://www.biotek.com/scratchassay MultiFlo FX Multi-Mode Dispenser https://www.biotek.com/multiflofx Applications: https://www.biotek.com/applications/cell-migration-invasion.html

BioTek Instruments

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