The predominant signaling pathways involved in human embryonic stem cell (ESC) pluripotency are TGF-β, FGF and Wnt signaling pathways. This video describes how these pathways lead to the activation of 3 key transcription factors, which activate the transcription of ESC specific genes. Visit http://www.cellsignal.com to see antibodies directed against stem cell and lineage markers.
Cell ScienceMolecular Biology